Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4507497 | 0.84 | ALDH1A1 (0.45) | FUCA1ALDH1A1MEN1KMT2AGBA1 | |
| SCHEMBL31171560 | 0.83 | MAPT (0.43) | FUCA1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31171590 | 0.83 | MAPT (0.43) | FUCA1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31171510 | 0.83 | MAPT (0.43) | FUCA1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18930722 | 0.81 | ACHE (0.46) | FUCA1MAPTGAAOPRK1ELANE | |
| SCHEMBL17063291 | 0.81 | MEN1 (0.41) | FUCA1MAPTMEN1KMT2ATSHR | |
| SCHEMBL15866083 | 0.80 | FUCA1 (0.45) | FUCA1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31172293 | 0.80 | FUCA1 (0.45) | FUCA1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1189331 | 0.80 | GAA (0.39) | FUCA1MAPTMEN1KMT2ATSHR | |
| SCHEMBL30748878 | 0.80 | GAA (0.39) | FUCA1MAPTMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021094312-A1 | PYRROLIDINE AND BICYCLOHETEROARYL CONTAINING OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-05-20 | — | — | WO | disclosed |