SCHEMBL30748878

SCHEMBL30748878

CC1(C)CC(F)CN1Cc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.39
ELANE P08246 1/20 0.39
FUCA1 P04066 2/20 0.38
HSD11B1 P28845 2/20 0.38
ACHE P22303 1/20 0.38
SIGMAR1 Q99720 1/20 0.37
MAPT P10636 1/20 0.36
MEN1 O00255 1/20 0.36
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.36
AMPD2 Q01433 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31171606 0.81 MAPT (0.39) GAAELANEFUCA1MAPTMEN1
SCHEMBL18930722 0.81 ACHE (0.46) GAAELANEFUCA1ACHEMAPT
SCHEMBL19111473 0.81 JAK1 (0.40) GAAELANEFUCA1ACHE
SCHEMBL23377484 0.80 FUCA1 (0.45) GAAELANEFUCA1MAPTMEN1
SCHEMBL31190829 0.80 HSD11B1 (0.39) FUCA1HSD11B1SIGMAR1TSHR
SCHEMBL1189331 0.80 GAA (0.39) GAAELANEFUCA1ACHESIGMAR1
SCHEMBL21438350 0.79 GAA (0.38) GAAELANEFUCA1ACHESIGMAR1
SCHEMBL17069522 0.79 MEN1 (0.39) GAAELANEFUCA1ACHESIGMAR1
SCHEMBL21438880 0.78 GAA (0.37) GAAELANEFUCA1ACHESIGMAR1
SCHEMBL21468783 0.78 MEN1 (0.38) GAAELANEFUCA1ACHESIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT GAA 84/4885ELANE 7/4885FUCA1 241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.