Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2824399 | 0.80 | CA12 (0.56) | GSK3AGSK3BALDH1A1CA12CA2 | |
| SCHEMBL27295005 | 0.80 | MEN1 (0.54) | ALDH1A1MAPK1GAATSHR | |
| SCHEMBL8036307 | 0.79 | NPSR1 (0.47) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL1126831 | 0.77 | KDM4E (0.46) | ALDH1A1MAPK1GAAMAPTHSD17B10 | |
| SCHEMBL11110430 | 0.77 | GSK3A (0.48) | GSK3AGSK3BALDH1A1MAPK1CA12 | |
| SCHEMBL1093819 | 0.76 | GSK3A (0.44) | GSK3AGSK3BALDH1A1MAPK1MGAM | |
| SCHEMBL11539933 | 0.76 | TNF (0.50) | ALDH1A1GAAHSD17B10TSHR | |
| SCHEMBL563845 | 0.75 | ALDH1A1 (0.56) | GSK3AGSK3BALDH1A1 | |
| SCHEMBL10510973 | 0.74 | NPSR1 (0.53) | ALDH1A1MAPK1GAAMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL27678497 | 0.74 | ALDH1A1 (0.55) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228491-A1 | METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SCINNOHUB PHARMACEUTICAL CO., LTD. (CN) | 2024-07-11 | — | — | US | disclosed |
| US-20240228491-A1 | METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SCINNOHUB PHARMACEUTICAL CO., LTD. (CN) | 2024-07-11 | — | — | US | disclosed |
| US-20240228491-A1 | METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SCINNOHUB PHARMACEUTICAL CO., LTD. (CN) | 2024-07-11 | — | — | US | disclosed |
| EP-4332101-A1 | METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Scinnohub Pharmaceutical Co., Ltd (CN) | 2024-03-06 | — | — | EP | disclosed |
| CN-117295734-A | Methionine adenosyltransferase inhibitor, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-12-26 | — | — | CN | disclosed |
| US-20230002819-A1 | Methods for Biomolecular Sensing and Detection | UNIVERSAL SEQUENCING TECH CORPORATION (US) | 2023-01-05 | — | — | US | disclosed |
| WO-2022228515-A1 | METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 赛诺哈勃药业（成都）有限公司 | 2022-11-03 | — | — | WO | disclosed |
| EP-4017992-A1 | METHODS FOR BIOMOLECULAR SENSING AND DETECTION | Universal Sequencing Technology Corporation (US) | 2022-06-29 | — | — | EP | disclosed |
| CN-114667354-A | Method for biomolecule sensing and detection | 通用测序技术公司 | 2022-06-24 | — | — | CN | disclosed |
| WO-2021035221-A1 | METHODS FOR BIOMOLECULAR SENSING AND DETECTION | UNIVERSAL SEQUENCING TECHNOLOGY CORPORATION (US) | 2021-02-25 | — | — | WO | disclosed |
| US-6106999-A | SENSITIVITY TO GENERAL-PURPOSE VISIBLE LIGHT LASER, SO THAT HIGH-SPEED SCANNING EXPOSURE IS POSSIBLE BY LASER, AND EXTREMELY FINE HIGH RESOLUTION CAN BE OBTAINED; CAN BE USED FOR COATING OR PRINTING UNDER SAFELIGHT IRRADIATING CONDITIONS | MITSUI CHEMICALS (JP) | 2000-08-22 | — | — | US | disclosed |
| US-5977118-A | 6-substituted pyrazolo[3,4-d]pyrimidin-4-ones and compositions and methods of use thereof | SANOFI (FR) | 1999-11-02 | — | — | US | disclosed |
| WO-1999033461-A1 | C-10 CARBON-SUBSTITUTED ARTEMISININ-LIKE TRIOXANE COMPOUNDS HAVING ANTIMALARIAL, ANTIPROLIFERATIVE AND ANTITUMOUR ACTIVITIES | HAUSER, INC. (US) | 1999-07-08 | — | — | WO | disclosed |
| EP-0813527-A4 | 6-SUBSTITUTED PYRAZOLO 3,4-d] PYRIMIDIN-4-ONES AND COMPOSITIONS AND METHODS OF USE THEREOF | SANOFI WINTHROP INC (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0813527-A1 | 6-SUBSTITUTED PYRAZOLO 3,4-d] PYRIMIDIN-4-ONES AND COMPOSITIONS AND METHODS OF USE THEREOF | SANOFI PHARMACEUTICALS, INC. (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5656629-A | CYCLIC GUANOSINE MONOPHSPHATE-PHOSPHODIESTERASE INHIBITOR; USEFUL FOR TREATING HEART FAILURE AND/OR HYPERTENSION | SANOFI WINTHROP, INC. (US) | 1997-08-12 | — | — | US | disclosed |
| US-5599615-A | High performance electric contacts | XEROX CORPORATION (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996028429-A1 | 6-SUBSTITUTED PYRAZOLO [3,4-d] PYRIMIDIN-4-ONES AND COMPOSITIONS AND METHODS OF USE THEREOF | SANOFI WINTHROP, INC. (US) | 1996-09-19 | — | — | WO | disclosed |
| US-4148998-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1979-04-10 | — | — | US | disclosed |
| US-4136097-A | COPPER(II) COMPLEX AS PROMOTER | MCNEIL LABORATORIES, INC. (US) | 1979-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228491-A1 | METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | MAT1A, AMD1, MAT2B | GSK3A 1894/4885GSK3B 1732/4885ALDH1A1 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.