Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208101 | 0.79 | KDM4E (0.49) | KDM4ESMN1; SMN2HPGDALDH1A1TSHR | |
| SCHEMBL2337869 | 0.77 | GSK3A (0.50) | KDM4EGAAALDH1A1TSHRMAPK1 | |
| SCHEMBL8045914 | 0.77 | TSHR (0.50) | KDM4EHPGDALDH1A1TSHRLMNA | |
| SCHEMBL9522504 | 0.77 | KDM4E (0.43) | KDM4ESMN1; SMN2HPGDGAAALDH1A1 | |
| SCHEMBL27425338 | 0.76 | HPGD (0.40) | KDM4EHPGDGAAALDH1A1TSHR | |
| SCHEMBL26091147 | 0.74 | TSHR (0.54) | ALDH1A1TSHRLMNAMAPTHSD17B10 | |
| SCHEMBL2876964 | 0.74 | — | — | |
| SCHEMBL9206601 | 0.73 | GLS (0.41) | KDM4ESMN1; SMN2TSHRLMNAHSD17B10 | |
| SCHEMBL27667510 | 0.73 | KDM4E (0.36) | KDM4ESMN1; SMN2GAAALDH1A1TSHR | |
| SCHEMBL2853083 | 0.73 | ALDH1A1 (0.60) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113023678-B | Oxygen generation device of high-temperature carbonized ceramic-based molecular sieve membrane and use method thereof | 湖南万脉医疗科技有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-113023678-A | Oxygen generation device of high-temperature carbonized ceramic-based molecular sieve membrane and use method thereof | 湖南万脉医疗科技有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-113023679-A | Oxygen generation device of medical high-temperature molecular sieve membrane adsorption tower and use method thereof | 湖南万脉医疗科技有限公司 | 2021-06-25 | — | — | CN | claimed |
| EP-1054669-A2 | USE OF THIADIAZOLO[4,3-A]PYRIDINE DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 2000-11-29 | — | — | EP | claimed |
| WO-1999042089-A2 | USE OF THIADIAZOLO[4,3-A]PYRIDINE DERIVATIVES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-26 | — | — | WO | claimed |
| CN-113023679-B | Oxygen generation device of medical high-temperature molecular sieve membrane adsorption tower and use method thereof | 湖南万脉医疗科技有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-113023678-B | Oxygen generation device of high-temperature carbonized ceramic-based molecular sieve membrane and use method thereof | 湖南万脉医疗科技有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-113023679-A | Oxygen generation device of medical high-temperature molecular sieve membrane adsorption tower and use method thereof | 湖南万脉医疗科技有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-113023678-A | Oxygen generation device of high-temperature carbonized ceramic-based molecular sieve membrane and use method thereof | 湖南万脉医疗科技有限公司 | 2021-06-25 | — | — | CN | disclosed |
| US-9452168-B2 | Pyrrole antifungal agents | F2G LTD (GB) | 2016-09-27 | — | — | US | disclosed |
| US-20150238500-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-08-27 | — | — | US | disclosed |
| US-8993574-B2 | Pyrrole antifungal agents | F2G LTD (GB) | 2015-03-31 | — | — | US | disclosed |
| US-5252584-A | Antagonist for treating nervous system disorders | MERCK SHARP & DOHME LIMITED (GB) | 1993-10-12 | — | — | US | disclosed |
| EP-0489458-A1 | Hydroxyquinolone derivatives | MERCK SHARP & DOHME LTD. (GB) | 1992-06-10 | — | — | EP | disclosed |
| US-5091407-A | HETEROCYCLIC COMPOUNDS AS FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | disclosed |
| EP-0206523-B1 | HETEROCYCLIC COMPOUNDS AS FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-12-04 | — | — | EP | disclosed |
| US-4883807-A | PLANT GROWTH REGULATORS, SUBSTITUTED PYRROLE ESTERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-11-28 | — | — | US | disclosed |
| EP-0273572-A2 | Pyrrole derivatives and their use in agriculture | ZENECA LIMITED (GB) | 1988-07-06 | — | — | EP | disclosed |
| EP-0206523-A1 | Heterocyclic compounds as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-12-30 | — | — | EP | disclosed |
| US-4140793-A | HYPOGLYCEMIC AGENTS, ANTIULCER AGENTS | JOHN WYETH & BROTHER, LTD. (GB) | 1979-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150238500-A1 | PYRROLE ANTIFUNGAL AGENTS | FOXM1, PYCR1, ARG1 | KDM4E 1706/4885SMN1; SMN2 2831/4885HPGD 2971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.