SCHEMBL23387397

SCHEMBL23387397

CCCCCCCCCCCCCCCCCCOc1cc(C(=O)OCCC(=O)O[C@]2(O)C[C@H](n3cc(C)c(=O)[nH]c3=O)O[C@@H]2CO)cc(OCCCCCCCCCCCCCCCCCC)c1OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TK2 O00142 4/20 0.41
RNASE1 P07998 1/20 0.37
ABCG2 Q9UNQ0 3/20 0.36
ABCB1 P08183 1/20 0.36
CA12 O43570 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA5B Q9Y2D0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20518491 0.89 TK2 (0.41) TK2RNASE1ABCG2ABCB1CA12
SCHEMBL29529114 0.82 TK2 (0.40) TK2RNASE1CA12CA5ACA7
SCHEMBL20518472 0.78 TK2 (0.39) TK2RNASE1CA12CA5ACA7
SCHEMBL29834210 0.78 TK2 (0.42) TK2ABCG2ABCB1
SCHEMBL21625671 0.78 TK2 (0.62) TK2RNASE1
SCHEMBL30679319 0.77 TK2 (0.40) TK2RNASE1ABCG2ABCB1CA12
SCHEMBL29529678 0.74 TK2 (0.39) TK2RNASE1CA12CA5ACA7
SCHEMBL8356495 0.74 TK1 (0.47) RNASE1
SCHEMBL30937946 0.73 KDM4E (0.45)
SCHEMBL30608669 0.72 TK2 (0.39) TK2RNASE1ABCG2ABCB1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12209106-B2 Alkoxyphenyl derivatives, protected nucleosides and protected nucleotides, method for producing oligonucleotides, and method for removing substituents FUJIMOTO CHEMICALS CO., LTD. (KR) 2025-01-28 US disclosed
US-20240239834-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD., (JP) 2024-07-18 US disclosed
US-20210317159-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD. (JP) 2021-10-14 US disclosed
EP-3825300-A1 ALKOXYPHENYL DERIVATIVE, NUCLEOSIDE PROTECTOR, NUCLEOTIDE PROTECTOR, METHOD FOR PRODUCING OLIGONUCLEOTIDE, AND METHOD FOR REMOVING SUBSTITUENT Fujimoto Chemicals Co. Ltd. (JP) 2021-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239834-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT TK2 128/4885RNASE1 83/4885ABCG2 3014/4885
US-20210317159-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT TK2 128/4885RNASE1 83/4885ABCG2 3014/4885
US-12209106-B2 Alkoxyphenyl derivatives, protected nucleosides and protected nucleotides, method for producing oligonucleotides, and method for removing substituents ROS1, POLN, RNMT TK2 128/4885RNASE1 83/4885ABCG2 3014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.