SCHEMBL20518491

SCHEMBL20518491

CCCCCCCCCCCCCCCCCCOc1cc(COC(=O)CCC(=O)O[C@]2(O)C[C@H](n3cc(C)c(=O)[nH]c3=O)O[C@@H]2CO)cc(OCCCCCCCCCCCCCCCCCC)c1OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TK2 O00142 4/20 0.41
ABCG2 Q9UNQ0 3/20 0.38
ABCB1 P08183 1/20 0.38
CA12 O43570 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
BCHE P06276 1/20 0.35
TK1 P04183 2/20 0.34
RNASE1 P07998 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29834210 0.87 TK2 (0.42) TK2ABCG2ABCB1BCHETK1
SCHEMBL29529114 0.84 TK2 (0.40) TK2CA12CA5ACA7CA5B
SCHEMBL22472268 0.82 RNASE1 (0.51) TK2ABCG2ABCB1CA12CA5A
SCHEMBL13963213 0.80 TK2 (0.46) TK2ABCG2ABCB1TK1RNASE1
SCHEMBL16704789 0.80 TK2 (0.46) TK2ABCG2ABCB1TK1RNASE1
SCHEMBL20518472 0.79 TK2 (0.39) TK2CA12CA5ACA7CA5B
SCHEMBL30679319 0.78 TK2 (0.40) TK2ABCG2ABCB1CA12CA5A
SCHEMBL29529678 0.77 TK2 (0.39) TK2CA12CA5ACA7CA5B
SCHEMBL38654026 0.74 P2RY12 (0.36)
SCHEMBL8356495 0.74 TK1 (0.47) TK1RNASE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741411-A2 OLIGONUCLEOTIDE PRODUCTION METHOD, AND NUCLEOSIDE, NUCLEOTIDE, OR OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2026-05-13 EP disclosed
US-12269841-B2 Production method for oligonucleotides AJINOMOTO CO., INC. (JP) 2025-04-08 US disclosed
CN-113717239-B Precipitation accelerator and precipitation method using the same 味之素株式会社 2024-12-24 CN disclosed
EP-3263579-B1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED AJINOMOTO KK (JP) 2022-11-30 EP disclosed
EP-4049991-A1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED AJINOMOTO CO., INC. (JP) 2022-08-31 EP disclosed
EP-3925964-A1 PRODUCTION METHOD FOR OLIGONUCLEOTIDES AJINOMOTO CO., INC. (JP) 2021-12-22 EP disclosed
US-20210371450-A1 PRODUCTION METHOD FOR OLIGONUCLEOTIDES AJINOMOTO CO., INC. (JP) 2021-12-02 US disclosed
US-10919928-B2 Oligonucleotide production method, and nucleoside, nucleotide, or oligonucleotide AJINOMOTO CO., INC. (JP) 2021-02-16 US disclosed
WO-2020166705-A1 PRODUCTION METHOD FOR OLIGONUCLEOTIDES 味の素株式会社 2020-08-20 WO disclosed
EP-3398955-A1 OLIGONUCLEOTIDE PRODUCTION METHOD, AND NUCLEOSIDE, NUCLEOTIDE, OR OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2018-11-07 EP disclosed
US-20180282365-A1 OLIGONUCLEOTIDE PRODUCTION METHOD, AND NUCLEOSIDE, NUCLEOTIDE, OR OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2018-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180282365-A1 OLIGONUCLEOTIDE PRODUCTION METHOD, AND NUCLEOSIDE, NUCLEOTIDE, OR OLIGONUCLEOTIDE NUDT1, RNGTT, POLN TK2 92/4885ABCG2 2513/4885ABCB1 4420/4885
US-10919928-B2 Oligonucleotide production method, and nucleoside, nucleotide, or oligonucleotide POLL, POLM, NUDT1 TK2 224/4885ABCG2 2791/4885ABCB1 4611/4885
US-20210371450-A1 PRODUCTION METHOD FOR OLIGONUCLEOTIDES RNGTT, DCLRE1B, PHOSPHO1 TK2 550/4885ABCG2 3527/4885ABCB1 4535/4885
US-12269841-B2 Production method for oligonucleotides RNGTT, DCLRE1B, PHOSPHO1 TK2 550/4885ABCG2 3527/4885ABCB1 4535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.