SCHEMBL20518472

SCHEMBL20518472

CCCCCCCCCCCCCCCCCCOc1ccc(C(NC(=O)CCC(=O)O[C@]2(O)C[C@H](n3cc(C)c(=O)[nH]c3=O)O[C@@H]2CO)c2ccccc2)c(OCCCCCCCCCCCCCCCCCC)c1OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TK2 O00142 3/20 0.39
RNASE1 P07998 1/20 0.35
CA12 O43570 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
TK1 P04183 2/20 0.34
TOP2A P11388 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13963222 0.82 RNASE1 (0.46) TK2RNASE1TK1
SCHEMBL20518491 0.79 TK2 (0.41) TK2RNASE1CA12CA5ACA7
SCHEMBL23387397 0.78 TK2 (0.41) TK2RNASE1CA12CA5ACA7
SCHEMBL23387096 0.76 TK2 (0.40) TK2RNASE1CA12CA5ACA7
SCHEMBL13837083 0.76 RNASE1 (0.39) TK2RNASE1
SCHEMBL30396393 0.74
SCHEMBL29529114 0.73 TK2 (0.40) TK2RNASE1CA12CA5ACA7
SCHEMBL30679319 0.73 TK2 (0.40) TK2RNASE1CA12CA5ACA7
SCHEMBL13837086 0.72 TK2 (0.37) TK2RNASE1
SCHEMBL29834210 0.71 TK2 (0.42) TK2TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741411-A2 OLIGONUCLEOTIDE PRODUCTION METHOD, AND NUCLEOSIDE, NUCLEOTIDE, OR OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2026-05-13 EP disclosed
US-10919928-B2 Oligonucleotide production method, and nucleoside, nucleotide, or oligonucleotide AJINOMOTO CO., INC. (JP) 2021-02-16 US disclosed
EP-3398955-A1 OLIGONUCLEOTIDE PRODUCTION METHOD, AND NUCLEOSIDE, NUCLEOTIDE, OR OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2018-11-07 EP disclosed
US-20180282365-A1 OLIGONUCLEOTIDE PRODUCTION METHOD, AND NUCLEOSIDE, NUCLEOTIDE, OR OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2018-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180282365-A1 OLIGONUCLEOTIDE PRODUCTION METHOD, AND NUCLEOSIDE, NUCLEOTIDE, OR OLIGONUCLEOTIDE NUDT1, RNGTT, POLN TK2 92/4885RNASE1 251/4885CA12 3989/4885
US-10919928-B2 Oligonucleotide production method, and nucleoside, nucleotide, or oligonucleotide POLL, POLM, NUDT1 TK2 224/4885RNASE1 89/4885CA12 4339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.