Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4627196 | 0.94 | ESR1 (0.52) | ESR1KMT2AALDH1A1MEN1CYP3A4 | |
| SCHEMBL4628564 | 0.94 | KMT2A (0.48) | ESR1KMT2AALDH1A1HTR4MEN1 | |
| SCHEMBL4625675 | 0.94 | CYP4F2 (0.43) | ESR1KMT2AALDH1A1MEN1CYP3A4 | |
| SCHEMBL233745 | 0.94 | ALDH1A1 (0.44) | ESR1KMT2AALDH1A1HTR4MEN1 | |
| SCHEMBL4628595 | 0.91 | ESR1 (0.39) | ESR1KMT2AALDH1A1HTR4MEN1 | |
| SCHEMBL20695623 | 0.90 | KMT2A (0.47) | KMT2AALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL4626026 | 0.90 | ESR1 (0.41) | ESR1KMT2AALDH1A1HTR4MEN1 | |
| SCHEMBL4626833 | 0.90 | THRA (0.39) | ESR1KMT2AALDH1A1HTR4MEN1 | |
| SCHEMBL4628682 | 0.87 | CYP4F2 (0.41) | ESR1KMT2AALDH1A1HTR4MEN1 | |
| SCHEMBL4628042 | 0.87 | CYP4F2 (0.41) | ESR1KMT2AALDH1A1HTR4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283222-B9 | METHOD FOR PRODUCING A SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION | TOHO TITANIUM CO LTD (JP) | 2019-11-13 | — | — | EP | disclosed |
| EP-1283222-B2 | METHOD FOR PRODUCING A SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION | TOHO TITANIUM CO LTD (JP) | 2019-03-27 | — | — | EP | disclosed |
| EP-2360190-B1 | SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME | TOHO TITANIUM CO LTD (JP) | 2015-10-14 | — | — | EP | disclosed |
| US-8648001-B2 | Aminosilane compounds, catalyst components and catalysts for olefin polymerization, and process for production of olefin polymers with the same | TOHO TITANIUM CO., LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| EP-1921092-B1 | CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING OLEFIN POLYMER USING THOSE | TOHO TITANIUM CO LTD (JP) | 2013-10-02 | — | — | EP | disclosed |
| EP-2636688-A1 | METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND OLEFIN POLYMERS | Toho Titanium Co., Ltd. (JP) | 2013-09-11 | — | — | EP | disclosed |
| US-20130109789-A1 | OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-02 | — | — | US | disclosed |
| US-8426537-B2 | Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same | TOHO TITANIUM CO., LTD. (JP) | 2013-04-23 | — | — | US | disclosed |
| US-8247504-B2 | Catalyst component, catalyst for olefin polymerization, and process for producing olefin polymer using catalyst | Toho Titanium, Co.,. Ltd. (JP) | 2012-08-21 | — | — | US | disclosed |
| EP-1283222-B1 | SOLID CATALYST INGREDIENT AND CATALYST EACH FOR OLEFIN POLYMERIZATION AND PROPYLENE BLOCK COPOLYMER | TOHO TITANIUM CO LTD (JP) | 2012-07-04 | — | — | EP | disclosed |
| EP-1452548-A1 | POLYMERIZATION CATALYST FOR OLEFINS AND PROCESS FOR POLYMERIZATION OF OLEFINS | Toho Catalyst Co., Ltd. (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-6770586-B2 | Solid catalyst component and catalyst for olefins polymerization | TOHO TITANIUM CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |
| US-20040077488-A1 | Polymerization catalyst for olefins and process for polymerization of olefins | TOHO TITANIUM CO., LTD. (JP) | 2004-04-22 | — | — | US | disclosed |
| US-6670497-B2 | Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst | TOHO TITANIUM CO., LTD. (JP) | 2003-12-30 | — | — | US | disclosed |
| US-20030153454-A1 | Solid catalyst ingredient and catalyst each for olefin polymerization and propylene block copolymer | TOHO TITANIUM CO., LTD. (JP) | 2003-08-14 | — | — | US | disclosed |
| US-20030130109-A1 | Solid catalyst component and catalyst for olefins polymerization | TOHO TITANIUM CO., LTD (JP) | 2003-07-10 | — | — | US | disclosed |
| US-20030036594-A1 | Phthalic diester derivatives and electron donors | TOHO TITANIUM CO., LTD. (JP) | 2003-02-20 | — | — | US | disclosed |
| EP-1283222-A1 | SOLID CATALYST INGREDIENT AND CATALYST EACH FOR OLEFIN POLYMERIZATION AND PROPYLENE BLOCK COPOLYMER | Toho Catalyst Co., Ltd. (JP) | 2003-02-12 | — | — | EP | disclosed |
| EP-1209172-A1 | SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION | Toho Titanium Co., Ltd. (JP) | 2002-05-29 | — | — | EP | disclosed |
| EP-1188739-A1 | PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS | TOHO TITANIUM CO., LTD. (JP) | 2002-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036594-A1 | Phthalic diester derivatives and electron donors | HPD, ETFA, PPOX | ESR1 168/4885KMT2A 3313/4885ALDH1A1 725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.