Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23893577 | 0.89 | RAB9A (0.34) | APPALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL23395715 | 0.84 | ALDH1A1 (0.33) | APPALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL23395722 | 0.82 | ALDH1A1 (0.36) | APPALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL23395590 | 0.82 | NPC1 (0.33) | APPALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL23893478 | 0.81 | ALDH1A1 (0.33) | APPALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL23395563 | 0.77 | KDM4E (0.34) | APPALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL23893559 | 0.77 | NPC1 (0.32) | APPALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL23893560 | 0.76 | KDM4E (0.36) | APPALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL25898863 | 0.76 | ALDH1A1 (0.33) | APPALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL26292178 | 0.74 | RAB9A (0.42) | APPALDH1A1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889135-B1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-08-02 | — | — | EP | disclosed |
| EP-3583092-B1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-05-26 | — | — | EP | disclosed |