Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23395722 | 0.92 | ALDH1A1 (0.36) | KDM4ENPC1ALDH1A1GLAGAA | |
| SCHEMBL23395686 | 0.83 | APP (0.35) | KDM4ENPC1ALDH1A1GLAGAA | |
| SCHEMBL26292178 | 0.82 | RAB9A (0.42) | KDM4ENPC1ALDH1A1GLAGAA | |
| SCHEMBL23395657 | 0.82 | PTPN1 (0.49) | KDM4ENPC1ALDH1A1GLAGAA | |
| SCHEMBL23395715 | 0.78 | ALDH1A1 (0.33) | KDM4ENPC1ALDH1A1GLAGAA | |
| SCHEMBL23395599 | 0.77 | PDE4D (0.54) | PTPN1APPPDE4DCYP19A1 | |
| SCHEMBL23893577 | 0.77 | RAB9A (0.34) | KDM4ENPC1ALDH1A1GLAGAA | |
| SCHEMBL23395697 | 0.76 | APP (0.33) | KDM4ENPC1ALDH1A1GLAGAA | |
| SCHEMBL23395563 | 0.76 | KDM4E (0.34) | KDM4ENPC1ALDH1A1GLAGAA | |
| SCHEMBL23893559 | 0.76 | NPC1 (0.32) | KDM4ENPC1ALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889135-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |