Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23395865 | 0.87 | KMT2A (0.32) | KMT2APOLBL3MBTL1 | |
| SCHEMBL23396016 | 0.86 | CHEK2 (0.37) | KMT2AMEN1SRD5A1SRD5A2EPHX2 | |
| SCHEMBL23396270 | 0.75 | KMT2A (0.32) | KMT2A | |
| SCHEMBL23395884 | 0.74 | — | — | |
| SCHEMBL23396001 | 0.71 | — | — | |
| SCHEMBL23395912 | 0.68 | EPHX2 (0.41) | KMT2APOLBMEN1EPHX2 | |
| SCHEMBL23395958 | 0.68 | TDP2 (0.30) | — | |
| SCHEMBL23396015 | 0.68 | CA12 (0.43) | MAPT | |
| SCHEMBL23395885 | 0.67 | PLA2G2A (0.33) | KMT2APOLBMEN1MAPT | |
| SCHEMBL23395836 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230281-B1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | BAYER AG (DE) | 2021-05-26 | — | — | EP | disclosed |