Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23396146 | 0.86 | KMT2A (0.35) | SRD5A1MEN1KMT2ASRD5A2EPHX2 | |
| SCHEMBL23396270 | 0.82 | KMT2A (0.32) | KMT2A | |
| SCHEMBL23395912 | 0.80 | EPHX2 (0.41) | CHEK2CYP11B2HRH3MEN1KMT2A | |
| SCHEMBL23396295 | 0.76 | IKBKB (0.41) | CHEK2CYP11B2HRH3MEN1KMT2A | |
| SCHEMBL23395865 | 0.74 | KMT2A (0.32) | KMT2AF10PRSS1PRSS2PRSS3 | |
| SCHEMBL23396015 | 0.73 | CA12 (0.43) | — | |
| SCHEMBL23395836 | 0.72 | — | — | |
| SCHEMBL23395823 | 0.71 | P2RX3 (0.38) | P2RX3P2RX2 | |
| SCHEMBL23395885 | 0.71 | PLA2G2A (0.33) | MEN1KMT2AP2RX3P2RX2 | |
| SCHEMBL23395958 | 0.69 | TDP2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230281-B1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | BAYER AG (DE) | 2021-05-26 | — | — | EP | disclosed |