Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23396295 | 0.81 | IKBKB (0.41) | POLBMEN1KMT2A | |
| SCHEMBL23396103 | 0.66 | GRM5 (0.38) | SMN1; SMN2 | |
| SCHEMBL23396270 | 0.64 | KMT2A (0.32) | KMT2A | |
| SCHEMBL8464240 | 0.63 | CYP3A4 (0.36) | MEN1CYP3A4KMT2ATDP1 | |
| SCHEMBL6347273 | 0.61 | ABCG2 (0.58) | KDM4EMEN1ALDH1A1EGFRTP53 | |
| SCHEMBL15458149 | 0.61 | ALDH5A1 (0.61) | POLBKDM4EMEN1ALDH1A1EGFR | |
| SCHEMBL56283 | 0.57 | CA5A (0.30) | — | |
| SCHEMBL9812572 | 0.57 | ALDH5A1 (0.60) | KDM4EMEN1ALDH1A1EGFRTP53 | |
| SCHEMBL14495743 | 0.56 | CA5A (0.52) | MAPTPKMHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL21712104 | 0.56 | EPHX2 (0.58) | POLBEPHX2KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230281-B1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | BAYER AG (DE) | 2021-05-26 | — | — | EP | disclosed |