Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29720126 | 0.78 | MEN1 (0.36) | SMN1; SMN2 | |
| SCHEMBL2399333 | 0.70 | LOXL2 (0.52) | LOXL2F10NOS3NOS1NOS2 | |
| SCHEMBL27913568 | 0.69 | LOXL2 (0.50) | LOXL2F10NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL6442361 | 0.69 | LOXL2 (0.50) | LOXL2F10NOS3NOS1NOS2 | |
| SCHEMBL19774621 | 0.67 | ALDH1A1 (0.41) | KDM4ESMN1; SMN2 | |
| SCHEMBL28049358 | 0.67 | LOXL2 (0.52) | LOXL2F10NOS3NOS1NOS2 | |
| SCHEMBL25704003 | 0.66 | ALDH1A1 (0.47) | PLAUSMN1; SMN2THRATHRB | |
| SCHEMBL27499995 | 0.66 | LOXL2 (0.56) | LOXL2F10NOS3NOS1NOS2 | |
| SCHEMBL28159710 | 0.66 | LOXL2 (0.56) | LOXL2F10NOS3NOS1NOS2 | |
| SCHEMBL8015926 | 0.66 | NOS1 (0.38) | LOXL2F10NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3359154-B1 | WNT SIGNALING PATHWAY INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF | Suzhou Yunxuan Yiyao Keji Youxian Gongsi (CN) | 2021-05-26 | — | — | EP | disclosed |