Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17224805 | 0.78 | PLA2G10 (0.38) | PIM1PIM2PLA2G10KDM4EALDH1A1 | |
| SCHEMBL25184883 | 0.78 | MAPK8 (0.37) | MAPK8MAPK9KDM4EMAPK10MEN1 | |
| SCHEMBL29761327 | 0.76 | ALDH1A1 (0.36) | PLA2G10KDM4EALDH1A1MAPT | |
| SCHEMBL29058605 | 0.76 | ALDH1A1 (0.36) | PLA2G10KDM4EALDH1A1MAPT | |
| SCHEMBL29058918 | 0.70 | MEN1 (0.34) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL30254871 | 0.70 | MIF (0.38) | MAPK8MAPK9ROCK1 | |
| SCHEMBL28661087 | 0.69 | MAPK8 (0.36) | MAPK8MAPK9MAPTMAPK10MEN1 | |
| SCHEMBL20522637 | 0.69 | NPEPPS (0.37) | MEN1KMT2A | |
| SCHEMBL28627221 | 0.69 | HPGD (0.39) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL22499974 | 0.69 | MAPK8 (0.39) | PIM1PIM2MAPK8MAPK9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137456-B1 | PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-06-02 | — | — | EP | disclosed |