SCHEMBL25184883

SCHEMBL25184883

Cc1ccc2ccc(Cl)cc2c1-c1c(O)c(Cl)nn(C)c1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK8 P45983 5/20 0.37
▸ MAPK9 P45984 4/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ HSD11B1 P28845 1/20 0.35
▸ RXFP1 Q9HBX9 1/20 0.35
▸ TYMS P04818 1/20 0.35
▸ CASR P41180 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ PLK4 O00444 2/20 0.34
▸ AURKB Q96GD4 2/20 0.34
▸ AURKA O14965 1/20 0.34
▸ RPS6KA4 O75676 1/20 0.34
▸ MAPKAPK2 P49137 1/20 0.34
▸ GSK3B P49841 1/20 0.34
▸ MARK2 Q7KZI7 1/20 0.34
▸ BRSK1 Q8TDC3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21835397 0.90 MEN1 (0.33) MEN1KMT2ATYMSKDM4ELMNA
SCHEMBL29443524 0.90 MEN1 (0.33) MEN1KMT2ATYMSKDM4ELMNA
SCHEMBL30834467 0.88 TSHR (0.38) KMT2ATYMSCASRKDM4ELMNA
SCHEMBL25202984 0.86 HPGD (0.38) MEN1KMT2AHSD11B1KDM4EL3MBTL1
SCHEMBL29058918 0.80 MEN1 (0.34) MEN1KMT2AKDM4ELMNAHTT
SCHEMBL23398233 0.78 PIM1 (0.37) MAPK8MAPK9MEN1KMT2AKDM4E
Morpholine SCHEMBL28609463 0.76 ATM (0.36) MEN1KMT2AHSD11B1KDM4ELMNA
SCHEMBL28627221 0.76 HPGD (0.39) MEN1KMT2AKDM4ELMNAHTT
SCHEMBL29695283 0.75 KMT2A (0.37) MAPK8MEN1KMT2ARXFP1KDM4E
SCHEMBL20522637 0.74 NPEPPS (0.37) MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435044-B2 Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide FMC CORPORATION (US) 2025-10-07 — — US claimed
CN-113166075-B Pyridazinone herbicides and pyridazinone intermediates for preparing the same FMC公司 2024-10-25 — — CN claimed
US-20250304990-A1 HERBICIDE RESISTANCE SYNGENTA CROP PROTECTION AG (CH) 2025-10-02 — — US disclosed
CN-118265781-A Herbicide resistance 先正达农作物保护股份公司 2024-06-28 — — CN disclosed
WO-2024072768-A1 SUBSTITUTED FLUOROPYRIDINE AS HERBICIDES FMC CORPORATION (US) 2024-04-04 — — WO disclosed
WO-2023083972-A1 HERBICIDE RESISTANCE SYNGENTA CROP PROTECTION AG (CH) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435044-B2 Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide CBR3, CBR1, CYP4F3 MAPK8 2725/4885MAPK9 2818/4885MEN1 3526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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