SCHEMBL23398474

SCHEMBL23398474

CCn1nc(-c2cccc(C)c2)cc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.46
RAB9A P51151 2/20 0.46
KDM4E B2RXH2 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
TP53 P04637 1/20 0.42
CTSS P25774 1/20 0.42
CTSK P43235 1/20 0.42
TRPM8 Q7Z2W7 1/20 0.41
IDO1 P14902 1/20 0.41
METAP2 P50579 1/20 0.41
PDE4B Q07343 3/20 0.40
ADORA2A P29274 2/20 0.40
ADORA2B P29275 2/20 0.40
ADORA1 P30542 2/20 0.40
TLR8 Q9NR97 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400166 0.88 TLR8 (0.44) NPC1RAB9AKDM4EL3MBTL1SMN1; SMN2
SCHEMBL23402054 0.85 TLR8 (0.48) NPC1RAB9AKDM4EL3MBTL1SMN1; SMN2
SCHEMBL16664794 0.84 CTSS (0.44) KDM4ESMN1; SMN2ALDH1A1TP53CTSS
SCHEMBL23400239 0.84 NPC1 (0.43) NPC1RAB9AKDM4EL3MBTL1SMN1; SMN2
SCHEMBL1458784 0.83 SMN1; SMN2 (0.50) SMN1; SMN2ALDH1A1TP53ADORA2AADORA2B
SCHEMBL23400704 0.82 MEN1 (0.49) NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1
SCHEMBL23402778 0.79 NPC1 (0.49) NPC1RAB9AKDM4EL3MBTL1SMN1; SMN2
SCHEMBL12744791 0.77 CYP2C9 (0.54) KDM4EALDH1A1PDE4BADORA2AADORA2B
SCHEMBL4061285 0.77 NPC1 (0.47) NPC1RAB9AKDM4EL3MBTL1SMN1; SMN2
SCHEMBL23402124 0.76 ALDH1A1 (0.60) NPC1RAB9AKDM4EL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed