SCHEMBL23402126

SCHEMBL23402126

Cc1cccc(-c2cc(O)n(C(C)(C)C)n2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK2 O43353 1/20 0.48
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
KDM4E B2RXH2 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
LMNA P02545 1/20 0.44
SRC P12931 2/20 0.44
ABL1 P00519 1/20 0.44
IDO1 P14902 1/20 0.41
METAP2 P50579 1/20 0.41
P2RY6 Q15077 2/20 0.40
CNR1 P21554 2/20 0.39
CNR2 P34972 2/20 0.39
KMO O15229 2/20 0.39
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27009178 0.84 NPC1 (0.51) RIPK2NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL23400674 0.83 P2RY6 (0.43) NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1
SCHEMBL23399650 0.82 SMN1; SMN2 (0.42) RIPK2NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL4472873 0.81 RAB9A (0.58) RIPK2NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL27009185 0.80 RIPK2 (0.44) RIPK2NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL23402778 0.79 NPC1 (0.49) NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1
SCHEMBL23402124 0.76 ALDH1A1 (0.60) NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1
SCHEMBL27009181 0.76 KDM4E (0.41) RIPK2NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL27009180 0.76 NPC1 (0.41) RIPK2NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL23399849 0.75 RIPK2 (0.48) RIPK2NPC1RAB9AKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed