Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23400673 | 0.92 | HIF1A (0.46) | HIF1ACYP1A2CYP2C19CYP2C9POLB | |
| SCHEMBL23403375 | 0.87 | NPC1 (0.47) | HIF1APOLBKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL23403124 | 0.86 | ALDH1A1 (0.47) | HIF1ASMN1; SMN2MAPK1MAPTNPC1 | |
| SCHEMBL23402411 | 0.85 | HTT (0.43) | HIF1APOLBKDM4EAPEX1TDP1 | |
| SCHEMBL23398406 | 0.84 | ATM (0.47) | HIF1ACYP1A2CYP2C19CYP2C9POLB | |
| SCHEMBL14495717 | 0.83 | CYP2C19 (0.64) | HIF1ACYP1A2CYP2C19CYP2C9POLB | |
| SCHEMBL23399120 | 0.83 | MEN1 (0.49) | HIF1ACYP1A2CYP2C19CYP2C9NT5E | |
| SCHEMBL23401280 | 0.82 | HIF1A (0.44) | HIF1ACYP1A2CYP2C19CYP2C9POLB | |
| SCHEMBL23400016 | 0.81 | LMNA (0.48) | HIF1ACYP1A2CYP2C19CYP2C9POLB | |
| SCHEMBL23402885 | 0.79 | TDP2 (0.39) | CYP1A2CYP2C19CYP2C9KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |