SCHEMBL23401280

SCHEMBL23401280

Cc1ccccc1-c1c(C)c(O)nn1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.44
KDM4A O75164 2/20 0.42
LMNA P02545 2/20 0.41
TSHR P16473 1/20 0.41
CYP1A2 P05177 3/20 0.41
CYP2C19 P33261 2/20 0.41
CYP2C9 P11712 1/20 0.41
DCTPP1 Q9H773 1/20 0.40
USP2 O75604 1/20 0.40
NT5E P21589 1/20 0.40
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KMT2A Q03164 2/20 0.39
KDM4C Q9H3R0 1/20 0.39
FABP3 P05413 1/20 0.38
MAPT P10636 2/20 0.37
KDM6B O15054 1/20 0.37
ABCC4 O15439 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23398764 0.91 DCTPP1 (0.42) HIF1AKDM4ALMNADCTPP1KDM4E
SCHEMBL23400946 0.87 RPA1 (0.44) LMNATSHRUSP2POLBKMT2A
SCHEMBL23401677 0.86 HTT (0.44) HIF1ALMNAKMT2AMAPTALDH1A1
SCHEMBL23398780 0.84 ALDH1A1 (0.39) LMNATSHRUSP2KDM4EKMT2A
SCHEMBL23399539 0.83 HIF1A (0.44) HIF1AKDM4ALMNATSHRCYP1A2
SCHEMBL23403129 0.82 HIF1A (0.53) HIF1AKDM4ALMNATSHRCYP1A2
SCHEMBL23399201 0.82 LMNA (0.47) HIF1AKDM4ALMNATSHRCYP1A2
SCHEMBL23402541 0.82 ALDH1A1 (0.40) HIF1AKDM4ALMNATSHRCYP1A2
SCHEMBL23402837 0.81 CYP2C9 (0.55) HIF1ACYP1A2CYP2C19CYP2C9KDM4E
SCHEMBL23398455 0.78 TDP2 (0.39) LMNATSHRCYP1A2CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed