Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22951264 | 0.98 | CES2 (0.44) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL20535026 | 0.96 | CES2 (0.39) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL20535562 | 0.96 | CES2 (0.43) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL23405395 | 0.96 | CES2 (0.41) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL7687656 | 0.93 | CES2 (0.55) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL20535616 | 0.92 | APLNR (0.35) | CES2TDP1CA12CA2APLNR | |
| SCHEMBL25182441 | 0.92 | APLNR (0.35) | CES2TDP1CA12CA2APLNR | |
| SCHEMBL20535201 | 0.92 | APLNR (0.35) | CES2TDP1CA12CA2APLNR | |
| SCHEMBL20535618 | 0.92 | APLNR (0.35) | CES2TDP1CA12CA2APLNR | |
| SCHEMBL20573586 | 0.91 | CES2 (0.38) | CES2MEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609889-B1 | SMALL MOLECULES | UNIV DUNDEE (GB) | 2023-07-05 | — | — | EP | disclosed |
| US-20220127257-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2022-04-28 | — | — | US | disclosed |
| US-20220127257-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2022-04-28 | — | — | US | disclosed |
| US-11261179-B2 | Small molecules | UNIVERSITY OF DUNDEE (GB) | 2022-03-01 | — | — | US | disclosed |
| US-20210163469-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2021-06-03 | — | — | US | disclosed |
| US-20210163469-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2021-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127257-A1 | SMALL MOLECULES | ADRM1, MDM2, UBE2B | CES2 2101/4885MEN1 3139/4885THRB 808/4885 |
| US-11261179-B2 | Small molecules | ADRM1, MDM2, UBE2B | CES2 2101/4885MEN1 3139/4885THRB 808/4885 |
| US-20210163469-A1 | SMALL MOLECULES | ADRM1, MDM2, UBE2B | CES2 2101/4885MEN1 3139/4885THRB 808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.