Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL28088958 | 0.94 | — | — | |
| Guanidine SCHEMBL4648758 | 0.94 | HRH4 (0.38) | — | |
| Guanidine SCHEMBL29983942 | 0.93 | — | — | |
| Guanidine SCHEMBL5613752 | 0.93 | — | — | |
| Guanidine SCHEMBL11330173 | 0.93 | — | — | |
| Guanidine SCHEMBL2003 | 0.93 | — | — | |
| Guanidine SCHEMBL165720 | 0.93 | NOS2 (0.42) | — | |
| Guanidine SCHEMBL17967024 | 0.88 | HRH4 (0.35) | — | |
| Guanidine SCHEMBL25310528 | 0.86 | — | — | |
| Guanidine SCHEMBL66976 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122069924-A | Wide band gap perovskite solar cell and full perovskite laminated solar cell | 中国科学技术大学 | 2026-05-19 | — | — | CN | claimed |
| WO-2026087782-A1 | METHODS FOR DETECTING LEAD IN PLASTICS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2026-04-30 | — | — | WO | claimed |
| US-12594224-B2 | Oral care compositions and methods of use | COLGATE-PALMOLIVE COMPANY (US) | 2026-04-07 | — | — | US | claimed |
| US-20250286144-A1 | ELECTROLYTE SYSTEMS INCLUDING PERFORMANCE-ENHANCING ADDITIVES, AND ELECTROCHEMICAL CELLS INCLUDING THE SAME | Lyten, Inc. | 2025-09-11 | — | — | US | claimed |
| US-20250286141-A1 | ELECTROLYTE SYSTEMS INCLUDING PERFORMANCE-ENHANCING ADDITIVES, AND ELECTROCHEMICAL CELLS INCLUDING THE SAME | Lyten, Inc. | 2025-09-11 | — | — | US | claimed |
| US-12398222-B2 | Flame-retardant antimicrobial agent, preparation method therefor and use thereof, and flame-retardant antimicrobial thermoplastic resin composition | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2025-08-26 | — | — | US | claimed |
| US-20250154683-A1 | A NOVEL HIGH-PERFORMANCE PHOTODETECTOR BASED ON TWO-DIMENSIONAL PEROVSKITE CRYSTALS WITH ALTERNATING INTERLAYER CATIONS | CITY UNIVERSITY OF HONG KONG (HK) | 2025-05-15 | — | — | US | claimed |
| EP-4053177-B1 | FLAME-RETARDANT ANTIMICROBIAL AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF, AND FLAME-RETARDANT ANTIMICROBIAL THERMOPLASTIC RESIN COMPOSITION | CHINA PETROLEUM & CHEM CORP (CN) | 2025-01-22 | — | — | EP | claimed |
| CN-114206334-B | Process for preparing aminopyrimidine compounds | 艾库斯生物科学有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-114122259-B | Perovskite thin film solar cell and preparation method thereof | 杭州纤纳光电科技有限公司 | 2024-10-18 | — | — | CN | claimed |
| WO-2001038281-A1 | METHOD FOR OXIDATION OF XYLENE DERIVATIVES | GENERAL ELECTRIC COMPANY (US) | 2001-05-31 | — | — | WO | claimed |
| WO-2001038282-A1 | METHOD FOR OXIDATION OF XYLENE DERIVATIVES | GENERAL ELECTRIC COMPANY (US) | 2001-05-31 | — | — | WO | claimed |
| EP-0737060-B1 | CLEAR ANTIPERSPIRANT STICK | COLGATE PALMOLIVE CO (US) | 2000-11-02 | — | — | EP | claimed |
| WO-2000015190-A1 | COSMETIC COMPOSITIONS CONTAINING HIGHER ALKYL ACETATES AS EMOLLIENTS | EXXON CHEMICAL PATENTS INC. (US) | 2000-03-23 | — | — | WO | claimed |
| EP-0610031-B1 | Soldering flux | COOKSON GROUP PLC (GB) | 1999-09-22 | — | — | EP | claimed |
| US-5490979-A | Clear antiperspirant stick gelled with dibenzylidene sorbitol and containing a guanidine compound as gel stabilizer, and process of making same | THE MENNEN COMPANY (US) | 1996-02-13 | — | — | US | claimed |
| US-5382299-A | Soldering flux | COOKSON GROUP PLC (GB) | 1995-01-17 | — | — | US | claimed |
| EP-0610031-A1 | Soldering flux | COOKSON GROUP plc (GB) | 1994-08-10 | — | — | EP | claimed |
| US-4777297-A | ETHERIFICATION IN ALKALINE SOLUTION WITH BROMIDE OR IODIDE | MARUBISHI YUKA KOGYO KABUSHIKI KAISHA (JP) | 1988-10-11 | — | — | US | claimed |
| US-4246285-A | Skin conditioning compositions containing guanidine inorganic salts | THE PROCTER & GAMBLE COMPANY (US) | 1981-01-20 | — | — | US | claimed |