SCHEMBL23406368

SCHEMBL23406368

CC1(C)OB(c2c(Oc3ccc4ccccc4c3)cc(Cl)cc2Oc2ccc3ccccc3c2)OC1(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.46
LPL P06858 2/20 0.46
LIPG Q9Y5X9 2/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
SLC6A4 P31645 1/20 0.41
GAA P10253 1/20 0.41
RCE1 Q9Y256 1/20 0.41
CYP2A6 P11509 2/20 0.37
CYP1A2 P05177 1/20 0.37
PARG Q86W56 6/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PPARG P37231 1/20 0.35
NR1I2 O75469 1/20 0.35
HSD11B1 P28845 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
ALOX5 P09917 1/20 0.34
ENPP3 O14638 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23406341 0.76 SLC6A4 (0.46) LMNASLC6A4NR1I2HSD11B1
SCHEMBL23406401 0.76 SLC6A4 (0.46) LPLLIPGLMNAMAPTSLC6A4
SCHEMBL22159677 0.75 HTR2A (0.41) HTTLPLLIPGLMNAMAPT
SCHEMBL25101080 0.71 HTT (0.57) HTTLMNAMAPTSLC6A4GAA
SCHEMBL30207438 0.71 HTT (0.57) HTTLMNAMAPTSLC6A4GAA
SCHEMBL16139819 0.70 LPL (0.43) HTTLPLLIPGLMNASLC6A4
SCHEMBL22159668 0.69 DPP4 (0.43) LPLLIPGLMNAMAPTSLC6A4
SCHEMBL120527 0.68 LPL (0.75) LPLLIPG
SCHEMBL29392121 0.68 LPL (0.75) LPLLIPG
SCHEMBL1007854 0.68 LPL (0.60) LPLLIPGLMNAMAPTSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11600790-B2 Polycyclic aromatic compound for organic electroluminescent device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-03-07 US disclosed
US-11600790-B2 Polycyclic aromatic compound for organic electroluminescent device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-03-07 US disclosed
US-20210167288-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2021-06-03 US disclosed
US-20210167288-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2021-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210167288-A1 POLYCYCLIC AROMATIC COMPOUND ARNT, TYR, AHR HTT 701/4885LPL 3842/4885LIPG 3943/4885
US-11600790-B2 Polycyclic aromatic compound for organic electroluminescent device AOC2, TYR, BMI1 HTT 1021/4885LPL 3065/4885LIPG 2974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.