SCHEMBL2340745

SCHEMBL2340745

CCc1ccccc1P(c1ccccc1CC)c1ccccc1CC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.44
GABRB2 P47870 4/20 0.44
MGLL Q99685 1/20 0.40
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAOA P21397 1/20 0.36
CYP2D6 P10635 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29790848 1.00 GABRA1 (0.44) GABRA1GABRB2MGLLTP53MAPT
SCHEMBL20873227 0.97 GABRA1 (0.42) GABRA1GABRB2MGLLTP53MAPT
SCHEMBL20873233 0.87 CYP3A4 (0.42) GABRA1GABRB2MGLLTP53MAPT
SCHEMBL1727172 0.86 CYP3A4 (0.46) GABRA1GABRB2MGLLTP53MAPT
SCHEMBL5988443 0.86 CYP3A4 (0.46) GABRA1GABRB2MGLLTP53MAPT
SCHEMBL29595366 0.86 CYP3A4 (0.46) GABRA1GABRB2MGLLTP53MAPT
Hydrochloric Acid SCHEMBL29496457 0.84 CYP3A4 (0.44) GABRA1GABRB2MGLLTP53MAPT
Bromide SCHEMBL29496481 0.84 CYP3A4 (0.44) GABRA1GABRB2MGLLTP53MAPT
Iodide SCHEMBL8728751 0.84 CYP3A4 (0.44) GABRA1GABRB2MGLLTP53MAPT
Iodide SCHEMBL11355870 0.84 CYP3A4 (0.44) GABRA1GABRB2MGLLTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2708527-B1 ALDEHYDE COMPOUND PRODUCTION METHOD MITSUI CHEMICALS INC (JP) 2019-03-20 EP claimed
US-9227925-B2 Process for producing aldehyde compounds MITSUI CHEMICALS, INC. (JP) 2016-01-05 US claimed
US-20090054519-A1 DERIVATIVES OF MONOSACCHARIDES AS 5-LIPOXYGENASE INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2009-02-26 US claimed
US-20020137820-A1 Phosphorus compounds SANDOZ LTD. (CH) 2002-09-26 US claimed
US-12296304-B2 Membrane for water filtration AQUAPORIN A/S (DK) 2025-05-13 US disclosed
EP-4277731-B1 PROCESS FOR PREPARING A MEMBRANE AQUAPORIN AS (DK) 2024-10-09 EP disclosed
US-20240058768-A1 MEMBRANE FOR WATER FILTRATION AQUAPORIN A/S (DK) 2024-02-22 US disclosed
EP-4277731-A1 MEMBRANE FOR WATER FILTRATION Aquaporin A/S (DK) 2023-11-22 EP disclosed
EP-3663280-B1 METHOD FOR PRODUCING CYANONORBORNENE MITSUI CHEMICALS INC (JP) 2022-08-24 EP disclosed
CN-110944976-B Process for producing cyanonorbornene 三井化学株式会社 2022-08-09 CN disclosed
WO-2022152748-A1 MEMBRANE FOR WATER FILTRATION AQUAPORIN A/S (DK) 2022-07-21 WO disclosed
CN-114573422-A Treatment method of 3-methyl-3-butene-1-ol process waste liquid 万华化学集团股份有限公司 2022-06-03 CN disclosed
US-5481049-A REACTING CONJUGATED DIENE AND WATER IN PRESENCE OF CARBON DIOXIDE, USING PALLADIUM COMPOUND AND A FREE PHOSPHINE AS CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 1996-01-02 US disclosed
EP-0605735-A1 PROCESS FOR PRODUCING ALKADIENOL Mitsubishi Chemical Corporation (JP) 1994-07-13 EP disclosed
US-4418227-A Improved process for hydrogenating aldehydes and ketones by employing anionic group VIII metal hydride compositions as hydrogenation catalysts ALLIED CORPORATION (US) 1983-11-29 US disclosed
US-4268454-A Anionic group VIII metal hydride catalysts ALLIED CHEMICAL CORPORATION (US) 1981-05-19 US disclosed
US-4232170-A DECARBONYLATION, GROUP 8, METAL HYDRIDE COMPLEXES ALLIED CHEMICAL CORPORATION (US) 1980-11-04 US disclosed
US-4224458-A Process for homogeneous hydrogenation of polycyclic aromatic hydrocarbons ALLIED CHEMICAL CORPORATION (US) 1980-09-23 US disclosed
US-4175187-A REACTING ETHYLENE, SUBSTITUTED ETHYLENE WITH A SECONDARY AMINE AND A PALLADIUM CATALYST UNIVERSITY OF DELAWARE (US) 1979-11-20 US disclosed
US-4021381-A Integral-skinned polyurethane foam prepared in the presence of a phosphite or phosphine catalyst UNIVERSAL OIL PRODUCTS COMPANY (US) 1977-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054519-A1 DERIVATIVES OF MONOSACCHARIDES AS 5-LIPOXYGENASE INHIBITORS ALOX5, ALOX15, ALOX15B GABRA1 3601/4885GABRB2 2473/4885MGLL 63/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.