SCHEMBL2341192

SCHEMBL2341192

C=C(OC(C)=O)c1cc(OCc2ccccc2)c(OCc2ccccc2)c(OCc2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
KDM4E B2RXH2 1/20 0.48
PTPN1 P18031 1/20 0.47
LMNA P02545 1/20 0.47
BRD4 O60885 2/20 0.45
SMPD1 P17405 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
MAOB P27338 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2343079 0.83 MAOB (0.59) HPGDSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL487915 0.80 FOLH1 (0.48) HPGDSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL793724 0.79 MEN1 (0.65) HPGDSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL28236202 0.79 KDM4E (0.53) HPGDSMN1; SMN2NPC1RAB9AKDM4E
Hydrochloric Acid SCHEMBL514496 0.78 MEN1 (0.63) HPGDSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL14660694 0.78 MEN1 (0.63) HPGDSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL9680615 0.78 HPGD (0.58) HPGDSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL22555974 0.77 HPGD (0.54) HPGDSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL2338199 0.77 HPGD (0.76) HPGDSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL514495 0.77 GLRA1 (0.65) HPGDSMN1; SMN2NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8513395-B2 Method for the synthesis of anthocyanins BIOSYNTH AS (NO) 2013-08-20 US disclosed
US-8513395-B2 Method for the synthesis of anthocyanins BIOSYNTH AS (NO) 2013-08-20 US disclosed
EP-1891086-B1 METHOD FOR THE SYNTHESIS OF ANTHOCYANINS BIOSYNTH AS (NO) 2011-08-24 EP disclosed
US-20090111975-A1 METHOD FOR THE SYNTHESIS OF ANTHOCYANINS BIOSYNTH AS (NO) 2009-04-30 US disclosed
US-20090111975-A1 METHOD FOR THE SYNTHESIS OF ANTHOCYANINS BIOSYNTH AS (NO) 2009-04-30 US disclosed
EP-1891086-A1 METHOD FOR THE SYNTHESIS OF ANTHOCYANINS Biosynth AS (NO) 2008-02-27 EP disclosed
WO-2006134352-A1 METHOD FOR THE SYNTHESIS OF ANTHOCYANINS BIOSYNTH AS (NO) 2006-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090111975-A1 METHOD FOR THE SYNTHESIS OF ANTHOCYANINS POR, SPR, G6PD HPGD 1028/4885SMN1; SMN2 4251/4885NPC1 1527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.