Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23420047 | 0.92 | TP53 (0.56) | TP53MAPTGAAPOLBALDH1A1 | |
| SCHEMBL23419580 | 0.90 | TP53 (0.62) | TP53MAPTGAAPOLBMAPK1 | |
| SCHEMBL25014538 | 0.87 | MAPK1 (0.61) | MAPTGAAPOLBALDH1A1MAPK1 | |
| SCHEMBL25014540 | 0.84 | GAA (0.68) | TP53MAPTGAAPOLBALDH1A1 | |
| SCHEMBL2957421 | 0.83 | TP53 (0.62) | TP53MAPTGAAPOLBALDH1A1 | |
| SCHEMBL25014539 | 0.83 | KDM4E (0.69) | TP53MAPTGAAPOLBALDH1A1 | |
| SCHEMBL23419756 | 0.81 | ALDH1A1 (0.62) | MAPTGAAPOLBALDH1A1MAPK1 | |
| SCHEMBL25014493 | 0.78 | GAA (0.48) | TP53MAPTGAAPOLBMAPK1 | |
| SCHEMBL18929812 | 0.77 | HSP90AA1 (0.66) | ALDH1A1SMN1; SMN2KMT2AHSD17B10MEN1 | |
| SCHEMBL23419664 | 0.77 | TP53 (0.61) | TP53MAPTGAAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026791-A1 | PEPTIDES, COMPOUNDS, COMPOSITIONS AND METHODS FOR INHIBITING SOX9 | CRITICAL OUTCOME TECHNOLOGIES INC. (CA) | 2023-01-26 | — | — | US | disclosed |
| WO-2021097552-A1 | PEPTIDES, COMPOUNDS, COMPOSITIONS AND METHODS FOR INHIBITING SOX9 DIMERIZATION | CRITICAL OUTCOME TECHNOLOGIES INC. (CA) | 2021-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026791-A1 | PEPTIDES, COMPOUNDS, COMPOSITIONS AND METHODS FOR INHIBITING SOX9 | SOX18, SPEN, PAX3 | TP53 644/4885MAPT 4684/4885GAA 3873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.