Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534037 | 0.83 | ADRB2 (0.50) | IDO1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL10268290 | 0.83 | ADRB2 (0.50) | IDO1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL21505013 | 0.83 | ADRB2 (0.50) | IDO1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL17887406 | 0.83 | IDO1 (0.55) | IDO1RXRARXRBALOX5L3MBTL1 | |
| SCHEMBL3369539 | 0.83 | ADRB2 (0.54) | IDO1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL10037561 | 0.82 | IDO1 (0.59) | IDO1MEN1KMT2ARXRARXRB | |
| SCHEMBL260335 | 0.82 | IDO1 (0.63) | IDO1RXRARXRBALOX5L3MBTL1 | |
| SCHEMBL2293769 | 0.82 | IDO1 (0.68) | IDO1RXRARXRBALOX5L3MBTL1 | |
| SCHEMBL25623130 | 0.81 | IDO1 (0.53) | IDO1ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL7863823 | 0.81 | TSHR (0.54) | ADRB2ADRB1ADRB3LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210154202-A1 | SYNTHESIS OF DENTIMOL, AN ANTIGLAUCOMA DRUG | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2021-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210154202-A1 | SYNTHESIS OF DENTIMOL, AN ANTIGLAUCOMA DRUG | PTGIR, PTGIS, DNM1L | IDO1 4876/4885ADRB2 22/4885ADRB1 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.