Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10268290 | 0.85 | ADRB2 (0.50) | ADRB2ADRB1ADRB3LMNAIDO1 | |
| SCHEMBL21505013 | 0.85 | ADRB2 (0.50) | ADRB2ADRB1ADRB3LMNAIDO1 | |
| SCHEMBL3369539 | 0.85 | ADRB2 (0.54) | ADRB2ADRB1ADRB3LMNAIDO1 | |
| SCHEMBL4686836 | 0.84 | IDO1 (0.52) | LMNAIDO1ALDH1A1APPMAOB | |
| SCHEMBL134086 | 0.83 | IDO1 (0.61) | IDO1KMT2AAPPMAOBCHRM3 | |
| SCHEMBL23421663 | 0.83 | IDO1 (0.53) | ADRB2ADRB1ADRB3LMNAIDO1 | |
| SCHEMBL7863823 | 0.82 | TSHR (0.54) | ADRB2ADRB1ADRB3LMNAALDH1A1 | |
| SCHEMBL14545522 | 0.81 | ADRB2 (0.55) | ADRB2ADRB1ADRB3LMNAIDO1 | |
| SCHEMBL21578433 | 0.81 | IDO1 (0.58) | IDO1KMT2AAPPMAOBCHRM3 | |
| SCHEMBL9342899 | 0.81 | IDO1 (0.58) | IDO1KMT2AAPPMAOBCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974802-B | Preparation method of bisoprolol fumarate intermediate | 黑龙江珍宝岛药业股份有限公司鸡西分公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-115974802-A | Preparation method of bisoprolol fumarate intermediate | 黑龙江珍宝岛药业股份有限公司鸡西分公司 | 2023-04-18 | — | — | CN | disclosed |
| US-20120035214-A1 | RENIN INHIBITORS | MERCK CANADA INC. (CA) | 2012-02-09 | — | — | US | disclosed |
| EP-2413941-A1 | RENIN INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2012-02-08 | — | — | EP | disclosed |
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035214-A1 | RENIN INHIBITORS | REN, ACE, AGTR1 | ADRB2 59/4885ADRB1 30/4885ADRB3 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.