SCHEMBL23427468

SCHEMBL23427468

c1ccc(-c2ccc3oc4ccc(-c5c6ccccc6c(-c6ccc7c(c6)oc6cccc(-c8c9ccccc9c(-c9ccc%10oc%11ccc(-c%12ccccc%12)cc%11c%10c9)c9ccccc89)c67)c6ccccc56)cc4c3c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLA2G2A P14555 5/20 0.43
▸ PLA2G4A P47712 5/20 0.43
▸ PLA2G10 O15496 1/20 0.41
▸ MMP12 P39900 1/20 0.38
▸ MMP13 P45452 1/20 0.38
▸ HCRTR1 O43613 1/20 0.36
▸ NPC1 O15118 2/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ AHR P35869 2/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ MAPT P10636 2/20 0.36
▸ HPGD P15428 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ HSP90AA1 P07900 1/20 0.36
▸ HSP90AB1 P08238 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ ALOX5 P09917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23428159 0.99 PLA2G2A (0.42) PLA2G2APLA2G4APLA2G10MMP12MMP13
SCHEMBL23428259 0.99 PLA2G2A (0.42) PLA2G2APLA2G4APLA2G10MMP12MMP13
SCHEMBL24648204 0.95 PLA2G2A (0.41) PLA2G2APLA2G4APLA2G10MMP12MMP13
SCHEMBL23057108 0.95 PLA2G2A (0.43) PLA2G2APLA2G4APLA2G10MMP12MMP13
SCHEMBL23428258 0.95 MEN1 (0.39) PLA2G2APLA2G4APLA2G10MMP12MMP13
SCHEMBL26404286 0.95 PLA2G2A (0.41) PLA2G2APLA2G4APLA2G10MMP12MMP13
SCHEMBL23427719 0.95 MEN1 (0.39) PLA2G2APLA2G4APLA2G10MMP12MMP13
SCHEMBL23426926 0.95 MEN1 (0.39) PLA2G2APLA2G4APLA2G10MMP12MMP13
SCHEMBL23427963 0.95 MEN1 (0.39) PLA2G2APLA2G4APLA2G10MMP12MMP13
SCHEMBL25624568 0.95 MMP12 (0.40) PLA2G2APLA2G4APLA2G10MMP12MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11991927-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-05-21 — — US disclosed
US-11991927-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-05-21 — — US disclosed
US-20230301179-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-21 — — US disclosed
US-20230174560-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-08 — — US disclosed
US-20230174560-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-08 — — US disclosed
US-20210249610-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-08-12 — — US disclosed
US-20210167299-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-06-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210167299-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1A1, AOX1, OXER1 PLA2G2A 3297/4885PLA2G4A 3485/4885PLA2G10 3866/4885
US-20230174560-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, AOX1, CYP1A1 PLA2G2A 4295/4885PLA2G4A 4296/4885PLA2G10 4374/4885
US-20230301179-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, AOX1, CYP1A1 PLA2G2A 4258/4885PLA2G4A 4174/4885PLA2G10 4211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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