Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27043147 | 0.84 | ALOX15 (0.56) | ALOX15HTR2AADRB1HTR1AADRA2A | |
| SCHEMBL18658967 | 0.83 | ALOX15 (0.62) | ALOX15ACEKDM4EAPAF1POLB | |
| SCHEMBL19372678 | 0.75 | MAPT (0.67) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL27268943 | 0.74 | HTR2A (0.55) | ALOX15HTR2AADRB1HTR1AADRA2A | |
| SCHEMBL25802646 | 0.74 | KMT2A (0.52) | ALOX15HTR2AADRB1HTR1AADRA2A | |
| SCHEMBL9985687 | 0.73 | ALOX15 (0.60) | ALOX15ACEKDM4EAPAF1POLB | |
| SCHEMBL14595060 | 0.73 | KDM4E (0.63) | ALOX15ACEKDM4EAPAF1POLB | |
| SCHEMBL12950374 | 0.73 | ALOX15 (0.63) | ALOX15ACEKDM4EAPAF1POLB | |
| SCHEMBL16656706 | 0.73 | ALOX15 (0.63) | ALOX15ACEKDM4EAPAF1POLB | |
| SCHEMBL19296166 | 0.73 | KDM4E (0.63) | ALOX15ACEKDM4EAPAF1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350195-B1 | THE METHOD OF SYNTHESIS AND PURIFICATION OF A NUCLEOSIDE AND/OR A NUCLEOTIDE, A MODIFIED NUCLEOSIDE AND/OR NUCLEOTIDE, A DNA MOLECULE AND AN OLIGONUCLEOTIDE LIBRARY COMPRISING SAID MODIFIED NUCLEOSIDE AND/OR NUCLEOTIDE AND THE USE OF SAID OLIGONUCLEOTIDE LIBRARY | PURE BIOLOGICS SPOLKA AKCYJNA (PL) | 2021-06-02 | — | — | EP | disclosed |