Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR1E | P28566 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27043147 | 0.86 | ALOX15 (0.56) | KMT2AMEN1HTR2AADRB1HTR1A | |
| SCHEMBL8531507 | 0.84 | KMT2A (0.67) | KMT2AMEN1HCRTR1ALOX15MAPT | |
| SCHEMBL5613868 | 0.84 | KMT2A (0.67) | KMT2AMEN1HCRTR1ALOX15MAPT | |
| SCHEMBL5613870 | 0.84 | KMT2A (0.67) | KMT2AMEN1HCRTR1ALOX15MAPT | |
| Hydrochloric Acid SCHEMBL8531505 | 0.83 | KMT2A (0.66) | KMT2AMEN1HCRTR1ALOX15MAPT | |
| Hydrochloric Acid SCHEMBL8531502 | 0.83 | KMT2A (0.66) | KMT2AMEN1HCRTR1ALOX15MAPT | |
| Hydrochloric Acid SCHEMBL10641592 | 0.83 | KMT2A (0.66) | KMT2AMEN1HCRTR1ALOX15MAPT | |
| SCHEMBL26372592 | 0.82 | KDM4E (0.62) | KMT2AMEN1HCRTR1HTR2AADRB1 | |
| Abrine SCHEMBL161767 | 0.81 | ALOX15 (0.70) | KMT2AMEN1ALOX15ACEMAPT | |
| Abrine (L) SCHEMBL18777 | 0.81 | ALOX15 (0.70) | KMT2AMEN1ALOX15ACEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11692003-B2 | Mithramycin derivatives having increased selectivity and anti-cancer activity | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11692003-B2 | Mithramycin derivatives having increased selectivity and anti-cancer activity | MELK, TFAM, MDK | KMT2A 183/4885MEN1 797/4885HCRTR1 4791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.