Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.42 |
| ▸ | CCR8 | P51685 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.38 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23434905 | 0.83 | CCR1 (0.40) | CCR1CCR8L3MBTL1ALDH1A1SLC40A1 | |
| SCHEMBL23434806 | 0.82 | CCR1 (0.33) | CCR1CCR8L3MBTL1ALDH1A1SLC40A1 | |
| SCHEMBL2606635 | 0.82 | SLC40A1 (0.47) | CCR1CCR8L3MBTL1ALDH1A1SLC40A1 | |
| SCHEMBL10880120 | 0.82 | CCR1 (0.46) | CCR1CCR8L3MBTL1ALDH1A1SLC40A1 | |
| SCHEMBL12404704 | 0.79 | CCR1 (0.46) | CCR1CCR8L3MBTL1ALDH1A1SLC40A1 | |
| SCHEMBL29491307 | 0.79 | CCR1 (0.50) | CCR1CCR8L3MBTL1ALDH1A1SLC40A1 | |
| SCHEMBL24338471 | 0.79 | CCR1 (0.50) | CCR1CCR8L3MBTL1ALDH1A1SLC40A1 | |
| SCHEMBL585843 | 0.78 | PSMD14 (0.50) | CCR1CCR8L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL17926739 | 0.76 | CCR1 (0.36) | CCR1CCR8L3MBTL1ALDH1A1SLC40A1 | |
| SCHEMBL23979291 | 0.76 | CCR1 (0.56) | CCR1CCR8L3MBTL1ALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163454-A1 | SMALL MOLECULE INHIBITORS OF EBOLA AND LASSA FEVER VIRUSES AND METHODS OF USE | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2021-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163454-A1 | SMALL MOLECULE INHIBITORS OF EBOLA AND LASSA FEVER VIRUSES AND METHODS OF USE | CCR8, RPS8, HDHD5 | CCR1 13/4885CCR8 1/4885L3MBTL1 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.