Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23440876 | 0.85 | PTGDR2 (0.40) | HTTMAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL31548979 | 0.85 | FBP1 (0.43) | TDO2MAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL10878231 | 0.76 | AKR1C3 (0.49) | HTTTDO2PLA2G1BMAPTATG4B | |
| SCHEMBL23856076 | 0.76 | PTGDR2 (0.50) | HTTSMN1; SMN2LMNAGAA | |
| SCHEMBL16815421 | 0.73 | KDM4E (0.57) | TDO2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL16815420 | 0.73 | KDM4E (0.57) | TDO2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL28606592 | 0.72 | PTGER4 (0.72) | KDM4ELMNAPTGER1PTGER4PTGER3 | |
| SCHEMBL1944113 | 0.71 | CHRM3 (0.43) | MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL7916162 | 0.69 | HTT (0.55) | HTTPLA2G1BMAPTATG4BSMN1; SMN2 | |
| SCHEMBL22032605 | 0.68 | KDM4E (0.46) | HTTTDO2PLA2G1BMAPTATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11261154-B2 | Benzene derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-01 | — | — | US | disclosed |
| US-20210332009-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-10-28 | — | — | US | disclosed |
| EP-3831810-A1 | BENZENE DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2021-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11261154-B2 | Benzene derivative | PMP22, TMBIM6, MYT1 | HTT 1552/4885TDO2 3399/4885PLA2G1B 2941/4885 |
| US-20210332009-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | HTT 1552/4885TDO2 3399/4885PLA2G1B 2941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.