Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | SAT1 | P21673 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041842 | 0.93 | KDM4E (0.53) | KDM4EMAPK1HIF1AL3MBTL1PLA2G2A | |
| SCHEMBL25517756 | 0.93 | KDM4E (0.53) | KDM4EMAPK1HIF1AL3MBTL1PLA2G2A | |
| SCHEMBL13208810 | 0.89 | MTNR1A (0.42) | KDM4EMAPK1HIF1AL3MBTL1PLA2G2A | |
| SCHEMBL23451136 | 0.85 | TSHR (0.47) | KDM4EMAPK1HIF1APLA2G2ATSHR | |
| SCHEMBL23452878 | 0.85 | KDM4E (0.44) | KDM4EMAPK1HIF1APLA2G2ATSHR | |
| SCHEMBL17753875 | 0.83 | KDM4E (0.52) | KDM4EMAPK1HIF1AL3MBTL1TSHR | |
| SCHEMBL23442008 | 0.83 | PLA2G2A (0.44) | KDM4EMAPK1HIF1APLA2G2ATSHR | |
| SCHEMBL14265137 | 0.83 | PLA2G2A (0.44) | KDM4EMAPK1HIF1APLA2G2ATSHR | |
| SCHEMBL16982413 | 0.80 | ALDH1A1 (0.40) | KDM4EMAPK1HIF1AL3MBTL1PLA2G2A | |
| SCHEMBL23451009 | 0.80 | PLA2G2A (0.43) | KDM4EMAPK1HIF1APLA2G2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086978-A2 | BRANCHED TRIPLE LIPID-MODIFIED NUCLEIC ACID COMPOUNDS | DTX PHARMA, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023086979-A1 | STAGGERED TRIPLE LIPID-MODIFIED NUCLEIC ACID COMPOUNDS | DTX PHARMA, INC. (US) | 2023-05-19 | — | — | WO | disclosed |