SCHEMBL2344301

SCHEMBL2344301

CCCCC(Br)CCCCCO

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.55
ALDH1A1 P00352 3/20 0.55
HSD17B10 Q99714 1/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
TSHR P16473 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.50
LCK P06239 1/20 0.43
PPARD Q03181 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
ZDHHC7 Q9NXF8 1/20 0.39
DNM1 Q05193 2/20 0.39
CYP2D6 P10635 2/20 0.38
SPHK1 Q9NYA1 1/20 0.38
GMNN O75496 1/20 0.38
POLB P06746 1/20 0.38
THPO P40225 1/20 0.38
MTOR P42345 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8032127 0.95 LMNA (0.62) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL8858241 0.91 LMNA (0.55) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL2398065 0.91 LMNA (0.48) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL10859504 0.91 LMNA (0.55) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL9672577 0.91 LMNA (0.48) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL11874227 0.91 LMNA (0.55) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL28694080 0.86 LMNA (0.50) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL28589908 0.86 LMNA (0.50) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL28712088 0.86 LMNA (0.50) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL28433877 0.86 LMNA (0.50) LMNAALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903427-B Nitrate functionalized ionic liquid plasticizer and application thereof 中国科学院过程工程研究所 2024-04-16 CN disclosed
CN-116903427-A Nitrate functionalized ionic liquid plasticizer and application thereof 中国科学院过程工程研究所 2023-10-20 CN disclosed
US-8008358-B2 having terminal pentafluorosulfuranyl group or terminal trifluoromethoxy group and also a polar end group; fully degradable substitutes for perfluorinated surfactants; paint, fire-extinguishing composition, lubricant, cleaner, deicer, hydrophobicising for textile finishing or glass treatment; emulsifier MERCK PATENT GMBH (DE) 2011-08-30 US disclosed
EP-2208723-A1 Fluorosurfactants Merck Patent GmbH (DE) 2010-07-21 EP disclosed
EP-1833786-B1 FLUOROSURFACTANTS MERCK PATENT GMBH (DE) 2010-02-17 EP disclosed
US-20080149878-A1 having terminal pentafluorosulfuranyl group or terminal trifluoromethoxy group and also a polar end group; fully degradable substitutes for perfluorinated surfactants; paint, fire-extinguishing composition, lubricant, cleaner, deicer, hydrophobicising for textile finishing or glass treatment; emulsifier MERCK PATENT GMBH (DE) 2008-06-26 US disclosed
CN-101098853-A Fluorosurfactants MERCK PATENT GMBH (DE) 2008-01-02 CN disclosed
EP-1833786-A1 FLUOROSURFACTANTS Merck Patent GmbH (DE) 2007-09-19 EP disclosed
WO-2006072401-A1 FLUOROSURFACTANTS MERCK PATENT GMBH (DE) 2006-07-13 WO disclosed
US-7033765-B1 Site-specific drug delivery TORONTO RESEARCH CHEMICALS, INC. (CA) 2006-04-25 US disclosed
US-20060009375-A1 Site-specific drug delivery TORONTO RESEARCH CHEMICALS, INC. (CA) 2006-01-12 US disclosed
EP-0966304-B1 SITE-SPECIFIC DRUG DELIVERY DIME DAVID S (CA) 2005-05-25 EP disclosed
EP-0966304-A1 SITE-SPECIFIC DRUG DELIVERY Dime, David S. (CA) 1999-12-29 EP disclosed
WO-1998036777-A1 SITE-SPECIFIC DRUG DELIVERY DIME DAVID S (CA) 1998-08-27 WO disclosed
EP-0206810-A2 Acrylate compound and composition containing the same TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080149878-A1 having terminal pentafluorosulfuranyl group or terminal trifluoromethoxy group and also a polar end group; fully degradable substitutes for perfluorinated surfactants; paint, fire-extinguishing composition, lubricant, cleaner, deicer, hydrophobicising for textile finishing or glass treatment; emulsifier FFAR3, PFAS, FGR LMNA 2286/4885ALDH1A1 4087/4885HSD17B10 3133/4885
US-20060009375-A1 Site-specific drug delivery ABCG2, ABCB1, DHFR LMNA 768/4885ALDH1A1 353/4885HSD17B10 258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.