SCHEMBL23445288

SCHEMBL23445288

C1=Cc2c(oc3cccc(-c4cc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c5c6ccccc6c6ccccc6c5c4)c23)CC1

nearest known ligand 0.30

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.30
ADORA3 P0DMS8 1/20 0.30
ALOX15 P16050 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30
ADORA1 P30542 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
NFKB1 P19838 1/20 0.30
MAPK1 P28482 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
ATM Q13315 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26326502 0.89 TSHR (0.31) TSHRADORA3ALOX15ADORA2AADORA2B
SCHEMBL24971380 0.87 BACE1 (0.31) TSHRMAPT
SCHEMBL27279016 0.85 PLA2G2A (0.30)
SCHEMBL24972108 0.85 PLA2G2A (0.32)
SCHEMBL25653031 0.85 GPR55 (0.33) TSHRADORA3ALOX15ADORA2AADORA2B
SCHEMBL25652508 0.84 LMNA (0.31) TSHRMAPT
SCHEMBL26897346 0.84 TSHR (0.33) TSHRADORA3ALOX15ADORA2AADORA2B
SCHEMBL26292290 0.83 KDM4E (0.31) KDM4EALDH1A1TP53SMN1; SMN2HSD17B10
SCHEMBL26380975 0.82 MAPT (0.33) TSHRALOX15KDM4EALDH1A1TP53
SCHEMBL24971407 0.82 PLA2G2A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021107474-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2021-06-03 WO disclosed