⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234461 | 0.83 | ALDH1A1 (0.58) | — | |
| SCHEMBL24385153 | 0.73 | ALDH1A1 (0.50) | — | |
| SCHEMBL10887099 | 0.73 | ALDH1A1 (0.50) | — | |
| SCHEMBL712641 | 0.71 | — | — | |
| SCHEMBL107699 | 0.69 | — | — | |
| SCHEMBL941642 | 0.69 | — | — | |
| SCHEMBL13181134 | 0.69 | — | — | |
| SCHEMBL25191034 | 0.69 | — | — | |
| SCHEMBL9139528 | 0.69 | — | — | |
| SCHEMBL10053525 | 0.69 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156817-B1 | CONTROLLING PROTEIN LEVELS IN EUCARYOTIC ORGANISMS | WELLSTAT BIOCATALYSIS LLC (US) | 2008-08-27 | — | — | EP | claimed |
| EP-3676282-B1 | ANTI-CANCER AGENT | UNIV WOLLONGONG (AU) | 2024-11-06 | — | — | EP | disclosed |
| CN-111344298-B | Anticancer agent | 伍伦贡大学 | 2024-05-28 | — | — | CN | disclosed |
| US-11819489-B2 | Anti-cancer agent comprising a tumour homing peptide having arsenic bonded to cysteine residues | UNIVERSITY OF WOLLONGONG (AU) | 2023-11-21 | — | — | US | disclosed |
| CN-113173952-B | Ortho-dithiol reactive therapeutic probe for drug release monitoring and preparation | 济南大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113173952-A | Ortho-dithiol reactive therapeutic probe for drug release monitoring and preparation | 济南大学 | 2021-07-27 | — | — | CN | disclosed |
| US-20210205259-A1 | ANTI-CANCER AGENT | UNIVERSITY OF WOLLONGONG (AU) | 2021-07-08 | — | — | US | disclosed |
| CN-106892515-B | Method for treating high-concentration organic arsenic wastewater and recycling arsenic | 中国科学院生态环境研究中心 | 2021-03-02 | — | — | CN | disclosed |
| EP-3676282-A1 | ANTI-CANCER AGENT | University of Wollongong (AU) | 2020-07-08 | — | — | EP | disclosed |
| CN-111344298-A | Anticancer agent | 伍伦贡大学 | 2020-06-26 | — | — | CN | disclosed |
| EP-0946556-A4 | COMBINATORIAL PROCESS FOR PREPARING HYDROFUROQUINOLINE LIBRARIES | LILLY CO ELI (US) | 2001-07-04 | — | — | EP | disclosed |
| EP-1071958-A1 | METHODS FOR SUBSTRATE-LIGAND INTERACTION SCREENING | Arcaris, Inc. (US) | 2001-01-31 | — | — | EP | disclosed |
| WO-2000049417-A1 | METHODS FOR SUBSTRATE-LIGAND INTERACTION SCREENING | ARCARIS, INC. (US) | 2000-08-24 | — | — | WO | disclosed |
| WO-2000047220-A1 | CONTROLLING PROTEIN LEVELS IN EUCARYOTIC ORGANISMS | PROTEINIX, INC. (US) | 2000-08-17 | — | — | WO | disclosed |
| EP-0946556-A1 | COMBINATORIAL PROCESS FOR PREPARING HYDROFUROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027093-A1 | COMBINATORIAL PROCESS FOR PREPARING HYDROFUROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |
| US-5252466-A | Hybrids | BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0472658-A4 | FUSION PROTEINS HAVING AN IN VIVO POST-TRANSLATIONAL MODIFICATION SITE AND METHODS OF MANUFACTURE AND PURIFICATION | BIOTECHNOLOGY RES & DEV (US) | 1992-08-26 | — | — | EP | disclosed |
| EP-0472658-A1 | FUSION PROTEINS HAVING AN IN VIVO POST-TRANSLATIONAL MODIFICATION SITE AND METHODS OF MANUFACTURE AND PURIFICATION | BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION INCORPORATED (US) | 1992-03-04 | — | — | EP | disclosed |
| WO-1990014431-A1 | FUSION PROTEINS HAVING AN IN VIVO POST-TRANSLATIONAL MODIFICATION SITE AND METHODS OF MANUFACTURE AND PURIFICATION | BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION (US) | 1990-11-29 | — | — | WO | disclosed |