Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | BMP1 | P13497 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23446568 | 0.90 | ALDH1A1 (0.42) | LMNANOD1KMT2APOLBL3MBTL1 | |
| SCHEMBL16250326 | 0.85 | NOD1 (0.39) | NOD1KMT2APOLBL3MBTL1GNPAT | |
| SCHEMBL16250328 | 0.85 | NOD1 (0.39) | NOD1KMT2APOLBL3MBTL1GNPAT | |
| SCHEMBL22300359 | 0.81 | L3MBTL1 (0.34) | NOD1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL24235732 | 0.81 | CYP2C9 (0.41) | LMNANOD1KMT2APOLBL3MBTL1 | |
| SCHEMBL23280926 | 0.81 | MAPT (0.39) | LMNANOD1L3MBTL1MMP2MMP9 | |
| SCHEMBL17448284 | 0.80 | NOD1 (0.36) | NOD1KMT2APOLBL3MBTL1 | |
| SCHEMBL6027540 | 0.80 | SLC6A5 (0.46) | NOD1GNPAT | |
| SCHEMBL23446793 | 0.79 | L3MBTL1 (0.35) | NOD1KMT2APOLBL3MBTL1GNPAT | |
| SCHEMBL24966603 | 0.79 | L3MBTL1 (0.35) | NOD1KMT2APOLBL3MBTL1GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022022360-A1 | POLYETHYLENE GLYCOL CONJUGATE DRUG, AND PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2022-02-03 | — | — | WO | disclosed |
| WO-2021104120-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |