SCHEMBL2344955

SCHEMBL2344955

Oc1c(Cl)n(Br)c2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.38
ALDH1A1 P00352 7/20 0.38
KMT2A Q03164 6/20 0.38
HPGD P15428 4/20 0.38
MAPT P10636 4/20 0.38
HTT P42858 3/20 0.38
MEN1 O00255 3/20 0.38
POLB P06746 2/20 0.38
ESR2 Q92731 1/20 0.36
GAA P10253 2/20 0.36
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
GLA P06280 1/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
RCE1 Q9Y256 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2347898 0.77 ALDH1A1 (0.39) KDM4EALDH1A1KMT2AHPGDMAPT
SCHEMBL27947450 0.75 GPR3 (0.54) KDM4EALDH1A1KMT2AHPGDMAPT
SCHEMBL29163204 0.75 ALDH1A1 (0.38) KDM4EALDH1A1KMT2AHPGDMAPT
SCHEMBL7647965 0.71 GPR3 (0.52) KDM4EALDH1A1KMT2AMAPTMEN1
SCHEMBL11063007 0.71 POLB (0.46) KDM4EALDH1A1KMT2AHPGDMAPT
SCHEMBL28274689 0.69 ALDH1A1 (0.39) KDM4EALDH1A1KMT2AMAPTMEN1
SCHEMBL17094778 0.65 MAPT (0.40) KDM4EALDH1A1KMT2AHPGDMAPT
SCHEMBL16655565 0.64 KDM4E (0.57) KDM4EALDH1A1KMT2AHPGDMAPT
Biphenyl SCHEMBL14118924 0.64 KDM4E (0.46) KDM4EALDH1A1KMT2AHPGDMAPT
SCHEMBL31623977 0.62 KDM4E (0.39) KDM4EALDH1A1KMT2AHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8318452-B2 Solid culture medium for the detection and/or the species discrimination of glycopeptide-resistant enterococci RAMBACH ALAIN (FR) 2012-11-27 US claimed
EP-2041298-B1 SOLID CULTURE MEDIUM FOR THE DETECTION AND/OR THE SPECIES DISCRIMINATION OF GLYCOPEPTIDE-RESISTANT ENTEROCOCCI RAMBACH ALAIN (FR) 2010-12-22 EP claimed
EP-1348018-B1 CULTURE MEDIUM FOR DETECTING BACTERIA OF LISTERIA GENUS RAMBACH ALAIN (FR) 2010-07-14 EP claimed
US-20090280524-A1 SOLID CULTURE MEDIUM FOR THE DETECTION AND/OR THE SPECIES DISCRIMINATION OF GLYCOPEPTIDE-RESISTANT ENTEROCOCCI RAMBACH ALAIN 2009-11-12 US claimed
US-7351548-B2 Culture medium for detecting bacteria of listeria genus RAMBACH ALAIN 2008-04-01 US claimed
US-7198907-B2 culture for detecting Vibrio genus, containing a chromogenic agent chosen from beta-glucosidase substrates; diagnosing food poisioning and other gastrointestinal disorders SOUNDHOUND, INC. 2007-04-03 US claimed
EP-1453969-B1 METHOD FOR DETECTING MICROORGANISMS RAMBACH ALAIN (FR) 2006-10-11 EP claimed
EP-1397504-B1 CULTURE MEDIUM FOR DETECTING AND/OR DISCRIMINATING ENTEROCOCCUS AND METHOD THEREFOR RAMBACH ALAIN (FR) 2006-04-12 EP claimed
US-20050118667-A1 Method for detecting microorganisms RAMBACH ALAIN (FR) 2005-06-02 US claimed
US-20050009132-A1 Culture medium for detecting and/or discriminating enterococcus and method therefor RAMBACH ALAIN (FR) 2005-01-13 US claimed
US-20040265946-A1 Vibrio bacteria detection and/or differentiation SOUNDHOUND, INC. 2004-12-30 US claimed
EP-1297177-B1 VIBRIO BACTERIA DETECTION AND/OR DIFFERENTIATION RAMBACH ALAIN (FR) 2004-11-24 EP claimed
US-20040072279-A1 Culture medium for detecting bacteria of listeria genus RAMBACH ALAIN (FR) 2004-04-15 US claimed
US-6165743-A Culture medium for revealing enterohemorrhagic E. coli bacteria and procedure therefor RAMBACH ALAIN (FR) 2000-12-26 US claimed
US-5962251-A INTRODUCING AT LEAST TWO CHROMOGENS WHICH ARE ENZYME SUBSTRATES FOR A MICROORGANISM STRAIN INTO CULTURE MEDIUM, IDENTIFYING ACCESSORY COLOR PRODUCED BY ENZYMATIC ACTIVITY RAMBACH ALAIN (FR) 1999-10-05 US claimed
EP-0711360-B1 Process for the identification of microorganisms using at least two chromogens RAMBACH ALAIN (FR) 1998-03-11 EP claimed
US-5716799-A QUALITATIVE COLORIMETRIC ANALYSIS RAMBACH ALAIN (FR) 1998-02-10 US claimed
EP-0711359-B1 MICROORGANISM IDENTIFICATION METHOD USING A MEDIUM CONTAINING ADDED CARBOHYDRATE RAMBACH ALAIN (FR) 1997-05-28 EP claimed
EP-2785857-B1 METHOD FOR DETECTING PATHOGENIC YERSINIA ENTEROCOLITICA BACTERIA RAMBACH ALAIN (FR) 2016-05-04 EP disclosed
EP-0711359-B1 MICROORGANISM IDENTIFICATION METHOD USING A MEDIUM CONTAINING ADDED CARBOHYDRATE RAMBACH ALAIN (FR) 1997-05-28 EP disclosed