Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1180653 | 0.78 | POLB (0.64) | POLBMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL30344008 | 0.78 | POLB (0.64) | POLBMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL28298165 | 0.76 | ABCB1 (0.50) | POLBMAPTTSHRKDM4ENPC1 | |
| SCHEMBL2347898 | 0.72 | ALDH1A1 (0.39) | POLBMAPTKMT2AKDM4ERAB9A | |
| SCHEMBL2424796 | 0.72 | P2RX4 (0.69) | POLBMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL2344955 | 0.71 | KDM4E (0.38) | POLBMAPTTSHRKMT2AKDM4E | |
| SCHEMBL29163204 | 0.71 | ALDH1A1 (0.38) | POLBMAPTKMT2AKDM4ERAB9A | |
| SCHEMBL27947450 | 0.71 | GPR3 (0.54) | MAPTKMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL27504693 | 0.68 | ALDH1A1 (0.54) | POLBMAPTTSHRKMT2AKDM4E | |
| SCHEMBL31668450 | 0.68 | ALDH1A1 (0.54) | POLBMAPTTSHRKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459349-A | A 2-NAPHTHYL-4,5-DIPHENYLIMIDAZOLYL DIMER, UNSATURATED MONOMER | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1984-07-10 | — | — | US | disclosed |