Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2349793 | 0.80 | NFE2L2 (0.33) | MAPTCYP3A4 | |
| SCHEMBL2164088 | 0.78 | CA12 (0.41) | ERN1MAPTMAPK1RAB9ANPC1 | |
| SCHEMBL2349873 | 0.77 | TRPV4 (0.38) | TRPV4ERN1GAAKDM4EMAPT | |
| SCHEMBL4406700 | 0.77 | CYP3A4 (0.45) | MAPTNPC1SMN1; SMN2CYP3A4 | |
| SCHEMBL5207780 | 0.76 | TRPV4 (0.37) | TRPV4ERN1GAAKDM4EMAPT | |
| SCHEMBL1639475 | 0.74 | ERN1 (0.43) | TRPV4ERN1GAAKDM4EMAPT | |
| SCHEMBL27695180 | 0.74 | TRPV4 (0.36) | TRPV4ERN1GAAKDM4EMAPT | |
| SCHEMBL4396210 | 0.71 | KDM4E (0.39) | ERN1GAAKDM4EMAPTMAPK1 | |
| SCHEMBL28131218 | 0.71 | QDPR (0.36) | HTR2AHTR2C | |
| SCHEMBL29009367 | 0.70 | KDM4E (0.35) | KDM4EHTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749304-A1 | GHRELIN O-ACYLTRANSFERASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019149959-A1 | GHRELIN O-ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-08-08 | — | — | WO | disclosed |
| CN-101115723-B | Pyrazole carboxylic acid anilides, method for the production thereof and agents containing them for controlling pathogenic fungi | BASF AG (DE) | 2012-02-22 | — | — | CN | disclosed |
| US-8008232-B2 | Such as N-(3',4'-dichlorobiphenyl-2-yl)-5-chloro-1,3-dimethyl-1H-pyrazole-4-carboxamide; seeds | BASF AKTIENGESELLSCHAFT (DE) | 2011-08-30 | — | — | US | disclosed |
| US-20080153707-A1 | Pyrazolecarboxanilides, Process for Their Preparation and Compositions Comprising Them for Controlling Harmful Fungi | BASF AKITENGESELLSCHAFT (DE) | 2008-06-26 | — | — | US | disclosed |
| CN-101115723-A | Pyrazole carboxylic acid anilides, method for the production thereof and agents containing them for controlling pathogenic fungi | BASF AG (DE) | 2008-01-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153707-A1 | Pyrazolecarboxanilides, Process for Their Preparation and Compositions Comprising Them for Controlling Harmful Fungi | CBR3, C1S, PYM1 | TRPV4 3296/4885ERN1 283/4885GAA 4672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.