Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320901 | 0.87 | PRKCI (0.36) | KDM4EAPAF1RECQLPOLBMAPT | |
| SCHEMBL6609098 | 0.80 | APAF1 (0.48) | KDM4EAPAF1RECQLPOLBMAPT | |
| SCHEMBL6700169 | 0.76 | IAPP (0.50) | KDM4EAPAF1RECQLPOLBMAPT | |
| SCHEMBL20272550 | 0.73 | CYP1A2 (0.42) | KDM4EAPAF1RECQLPOLBMAPT | |
| SCHEMBL5202172 | 0.72 | ERCC1 (0.41) | POLBMAPTL3MBTL1ERCC1ERCC4 | |
| SCHEMBL5311363 | 0.72 | POLB (0.57) | KDM4EAPAF1RECQLPOLBMAPT | |
| SCHEMBL6005671 | 0.71 | CYP3A4 (0.52) | L3MBTL1ALOX15NR4A2TDP1 | |
| SCHEMBL9780834 | 0.71 | CYP3A4 (0.52) | L3MBTL1ALOX15NR4A2TDP1 | |
| SCHEMBL9972709 | 0.71 | APAF1 (0.36) | KDM4EAPAF1RECQLPOLBMAPT | |
| SCHEMBL1454266 | 0.70 | PPARG (0.53) | KDM4EAPAF1RECQLPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781675-B1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES INC (US) | 2014-03-26 | — | — | EP | disclosed |
| US-8389745-B2 | Phosphonate fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2013-03-05 | — | — | US | disclosed |
| US-20120116079-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | ELITECHGROUP MDX LLC | 2012-05-10 | — | — | US | disclosed |
| US-8008522-B2 | Phosphonate fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2011-08-30 | — | — | US | disclosed |
| US-20100261903-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | ELITECHGROUP MDX LLC | 2010-10-14 | — | — | US | disclosed |
| US-7767834-B2 | Phosphonylated fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2010-08-03 | — | — | US | disclosed |
| US-7671218-B2 | Phosphonate fluorescent dyes and conjugates | Elitech Holdings B.V. (NL) | 2010-03-02 | — | — | US | disclosed |
| EP-1991552-A2 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | Epoch Biosciences, Inc. (US) | 2008-11-19 | — | — | EP | disclosed |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| WO-2007098182-A2 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2007-08-30 | — | — | WO | disclosed |
| US-20070172832-A1 | Phosphonate fluorescent dyes and conjugates | EPOCH BIOSCIENCES, INC. (US) | 2007-07-26 | — | — | US | disclosed |
| EP-1781675-A2 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | Epoch Biosciences, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20060199955-A1 | Phosphonylated fluorescent dyes and conjugates | EPOCH BIOSCIENCES, INC. (US) | 2006-09-07 | — | — | US | disclosed |
| WO-2006020947-A2 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261903-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | PHOSPHO1, PFAS, PHPT1 | KDM4E 4173/4885APAF1 3605/4885RECQL 1785/4885 |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | PHOSPHO1, PFAS, PHPT1 | KDM4E 3818/4885APAF1 3429/4885RECQL 2405/4885 |
| US-20070172832-A1 | Phosphonate fluorescent dyes and conjugates | PHOSPHO1, PFAS, PHPT1 | KDM4E 4173/4885APAF1 3605/4885RECQL 1785/4885 |
| US-20060199955-A1 | Phosphonylated fluorescent dyes and conjugates | PHOSPHO1, PFAS, PHPT1 | KDM4E 3818/4885APAF1 3429/4885RECQL 2405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.