Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25997464 | 0.90 | ITGB3 (0.39) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL23419323 | 0.88 | MAPT (0.44) | MAPTNR1H4MEN1KMT2AALDH1A1 | |
| SCHEMBL25997471 | 0.77 | ITGB3 (0.37) | MAPTNPC1RAB9AHDAC6TP53 | |
| SCHEMBL29761153 | 0.76 | ALDH1A1 (0.60) | MAPTNR1H4MEN1KMT2AALDH1A1 | |
| SCHEMBL17445577 | 0.76 | ALDH1A1 (0.60) | MAPTNR1H4MEN1KMT2AALDH1A1 | |
| SCHEMBL23419400 | 0.73 | MAPT (0.42) | MAPTNR1H4MEN1KMT2AALDH1A1 | |
| SCHEMBL26082908 | 0.73 | CYP19A1 (0.60) | MAPTNR1H4MEN1KMT2AALDH1A1 | |
| SCHEMBL23419434 | 0.73 | ITGB3 (0.37) | MAPTNPC1RAB9AHDAC6TP53 | |
| SCHEMBL22386529 | 0.72 | MAPT (0.43) | MAPTNR1H4MEN1KMT2AALDH1A1 | |
| SCHEMBL26082647 | 0.72 | CYP19A1 (0.57) | MAPTNR1H4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265503-A1 | CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-08-24 | — | — | US | disclosed |
| WO-2021104845-A1 | CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-03 | — | — | WO | disclosed |