Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.31 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25997471 | 0.91 | ITGB3 (0.37) | ITGB3ITGA2BHDAC6TP53TAS1R3 | |
| SCHEMBL23419323 | 0.84 | MAPT (0.44) | ITGB3ITGA2BHDAC6TP53MAPT | |
| SCHEMBL23453246 | 0.82 | ITGB3 (0.35) | ITGB3ITGA2BITGB1ITGA4ITGB7 | |
| SCHEMBL31135859 | 0.81 | HSPD1 (0.40) | HDAC6TP53HPSEMAPTNPC1 | |
| SCHEMBL22371415 | 0.81 | HSPD1 (0.40) | HDAC6TP53HPSEMAPTNPC1 | |
| SCHEMBL25997464 | 0.74 | ITGB3 (0.39) | ITGB3ITGA2BHDAC6TP53TAS1R3 | |
| SCHEMBL23453356 | 0.73 | MAPT (0.41) | HDAC6TP53MAPTNPC1RAB9A | |
| SCHEMBL24240023 | 0.70 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL25997472 | 0.70 | HPSE (0.49) | TP53HPSEMAPTNPC1RAB9A | |
| SCHEMBL24240040 | 0.70 | MAPT (0.36) | TP53MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12031178-B2 | Cyclooctatetraene containing dyes and compositions | ILLUMINA CAMBRIDGE LIMITED (GB) | 2024-07-09 | — | — | US | disclosed |
| US-20230265503-A1 | CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-08-24 | — | — | US | disclosed |
| US-20230265502-A1 | CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-08-24 | — | — | US | disclosed |
| US-20210155983-A1 | CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-05-27 | — | — | US | disclosed |