Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SLC26A6 | Q9BXS9 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23453709 | 0.84 | P4HTM (0.47) | NPC1CYP1A2CYP2C19HSD17B10LMNA | |
| SCHEMBL6418611 | 0.80 | AR (0.49) | POLBTP53SLC26A6NPC1RAB9A | |
| SCHEMBL23453730 | 0.77 | NPC1 (0.46) | POLBTP53SLC26A6NPC1RAB9A | |
| SCHEMBL5317799 | 0.76 | TRPM8 (0.49) | POLBTP53NPC1RAB9AMAPK1 | |
| SCHEMBL22609318 | 0.74 | MEN1 (0.51) | POLBTP53SLC26A6PDE4BNPC1 | |
| SCHEMBL6417909 | 0.73 | MAPT (0.49) | POLBTP53NPC1RAB9ALMNA | |
| Hexane SCHEMBL23453727 | 0.73 | NPC1 (0.42) | POLBTP53SLC26A6NPC1RAB9A | |
| SCHEMBL11247013 | 0.72 | MAPT (0.71) | POLBNPC1RAB9AKCNQ3KCNQ2 | |
| SCHEMBL6108908 | 0.72 | PDE4D (0.56) | POLBRAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5317300 | 0.71 | HDAC6 (0.54) | POLBTP53NPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | ORFAN BIOTECH SL (ES) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | PNPO, XDH, GLS | POLB 1927/4885TP53 3308/4885SLC26A6 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.