Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351745 | 0.86 | ALDH1A1 (0.58) | TRPM8MAPTKDM4ENPC1RAB9A | |
| SCHEMBL5317300 | 0.81 | HDAC6 (0.54) | TRPM8POLBMAPTKDM4ENPC1 | |
| SCHEMBL19805499 | 0.78 | KDM4E (0.49) | TRPM8POLBMAPTKDM4ENPC1 | |
| SCHEMBL6418611 | 0.78 | AR (0.49) | TRPM8POLBMAPTKDM4ENPC1 | |
| SCHEMBL6417909 | 0.77 | MAPT (0.49) | TRPM8POLBMAPTKDM4ENPC1 | |
| SCHEMBL23453719 | 0.76 | POLB (0.52) | POLBMAPTKDM4ENPC1RAB9A | |
| SCHEMBL15497074 | 0.76 | POLB (0.46) | TRPM8POLBMAPTKDM4ENPC1 | |
| SCHEMBL5731634 | 0.76 | RAB9A (0.61) | POLBNPC1RAB9ASMN1; SMN2GRM6 | |
| SCHEMBL26102684 | 0.76 | MAPT (0.48) | TRPM8POLBMAPTKDM4ENPC1 | |
| SCHEMBL6108908 | 0.76 | PDE4D (0.56) | POLBMAPTKDM4ERAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079086-A1 | PYRAZOLOALKYL SUBSTITUTED IMIDAZO RING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-07-12 | — | — | WO | disclosed |