Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2404815 | 0.78 | SLC6A2 (0.44) | P2RX7S100A4ADORA3ARHSD11B1 | |
| Hydrochloric Acid SCHEMBL1992094 | 0.76 | P2RX7 (0.34) | P2RX7HTR2CGLSMAOBACHE | |
| SCHEMBL29908700 | 0.74 | S100A4 (0.44) | P2RX7S100A4ADORA3ARHSD11B1 | |
| SCHEMBL18988275 | 0.74 | S100A4 (0.44) | P2RX7S100A4ADORA3ARHSD11B1 | |
| SCHEMBL1986900 | 0.73 | MAOB (0.51) | P2RX7MAOBACHE | |
| SCHEMBL1987089 | 0.73 | MAOB (0.51) | P2RX7MAOBACHE | |
| SCHEMBL6858417 | 0.73 | MAOB (0.51) | P2RX7MAOBACHE | |
| SCHEMBL20252628 | 0.72 | P2RX7 (0.51) | P2RX7ADORA3ARHSD11B1AKR1C3 | |
| SCHEMBL8695216 | 0.72 | P2RX7 (0.51) | P2RX7ADORA3ARHSD11B1AKR1C3 | |
| Hydrochloric Acid SCHEMBL1988599 | 0.72 | MAOB (0.50) | P2RX7MAOBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2657221-A1 | Preparation of rasagiline and salts thereof | Dr. Reddy's Laboratories Ltd. (IN) | 2013-10-30 | — | — | EP | claimed |
| US-20110218360-A1 | PREPARATION OF RASAGILINE AND SALTS THEREOF | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-09-08 | — | — | US | claimed |
| EP-2358658-A2 | PREPARATION OF RASAGILINE AND SALTS THEREOF | Dr. Reddy's Laboratories, Ltd. (IN) | 2011-08-24 | — | — | EP | claimed |
| WO-2010059913-A2 | PREPARATION OF RASAGILINE AND SALTS THEREOF | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-05-27 | — | — | WO | claimed |
| EP-2657221-A1 | Preparation of rasagiline and salts thereof | Dr. Reddy's Laboratories Ltd. (IN) | 2013-10-30 | — | — | EP | disclosed |
| US-20110218360-A1 | PREPARATION OF RASAGILINE AND SALTS THEREOF | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-09-08 | — | — | US | disclosed |
| EP-2358658-A2 | PREPARATION OF RASAGILINE AND SALTS THEREOF | Dr. Reddy's Laboratories, Ltd. (IN) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010059913-A2 | PREPARATION OF RASAGILINE AND SALTS THEREOF | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218360-A1 | PREPARATION OF RASAGILINE AND SALTS THEREOF | RAB35, RAB27A, RAB5C | P2RX7 1540/4885S100A4 2886/4885ADORA3 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.