SCHEMBL2345803

SCHEMBL2345803

COC(OC)OC(=O)OC(OC)OC

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.32
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2345806 0.78
SCHEMBL784062 0.78
SCHEMBL13209260 0.76 ALDH1A1 (0.41) TSHRALDH1A1
SCHEMBL6270763 0.73 TSHR (0.41) TSHRALDH1A1
SCHEMBL8754584 0.73 TSHR (0.33) TSHR
SCHEMBL784026 0.71 MEN1 (0.38) TSHRALDH1A1
SCHEMBL784663 0.71
SCHEMBL984063 0.71 TSHR (0.36) TSHRALDH1A1
SCHEMBL29259026 0.71 SLC1A3 (0.35) TSHRALDH1A1SLC1A3SLC1A2SLC1A1
SCHEMBL4601055 0.69 ALDH1A1 (0.52) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113234054-A Dialkyl carbonates, methods of making and using the same 亨斯迈石油化学有限责任公司 2021-08-10 CN disclosed
US-9771458-B2 Reactive functional siloxane compositions MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2017-09-26 US disclosed
EP-2751162-B1 CATALYST SYSTEMS BASED ON PHENOLATE COMPLEXES FOR IMMORTAL RING-OPENING POLYMERISATION OF CYCLIC ESTERS AND CARBONATES TOTAL RES & TECHNOLOGY FELUY (BE) 2017-06-28 EP disclosed
US-20170010710-A1 TOUCH WINDOW AND DISPLAY WITH THE SAME LG INNOTEK CO., LTD. (KR) 2017-01-12 US disclosed
US-9447224-B2 Urethane (meth) acrylate monomer and production process thereof TOKUYAMA CORPORATION (JP) 2016-09-20 US disclosed
US-20160251483-A1 Reactive Functional Siloxane Compositions MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2016-09-01 US disclosed
US-8912290-B2 Process for producing functional siloxanes of controlled structure MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2014-12-16 US disclosed
EP-2424871-B1 CATALYTIC SYSTEMS FOR IMMORTAL RING-OPENING POLYMERISATION OF CYCLIC ESTERS AND CYCLIC CARBONATES. TOTAL RES & TECHNOLOGY FELUY (BE) 2014-10-29 EP disclosed
US-8829140-B2 Polysiloxane-polyorgano block copolymers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-09-09 US disclosed
US-20130267665-A1 PROCESS FOR PRODUCING FUNCTIONAL SILOXANES OF CONTROLLED STRUCTURE Momentive Performance Materlals GmbH (DE) 2013-10-10 US disclosed
US-20120296051-A1 POLYSILOXANE-POLYORGANO BLOCK COPOLYMERS MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2012-11-22 US disclosed
US-20120228567-A1 URETHANE (METH) ACRYLATE MONOMER AND PRODUCTION PROCESS THEREOF TOKUYAMA CORPORATION (JP) 2012-09-13 US disclosed
EP-1640357-B1 METHOD FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2011-08-31 EP disclosed
US-7652122-B2 Method for producing an aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-01-26 US disclosed
US-20070055042-A1 Method for producing an aromatic carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2007-03-08 US disclosed
EP-1640357-A1 METHOD FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2006-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120228567-A1 URETHANE (METH) ACRYLATE MONOMER AND PRODUCTION PROCESS THEREOF MTDH, PAM, ACR TSHR 3918/4885ALDH1A1 329/4885SLC1A3 1419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.