SCHEMBL23458348

SCHEMBL23458348

COCc1ccc(OC=O)c(OC)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.48
ALDH1A1 P00352 3/20 0.46
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
PPARA Q07869 1/20 0.46
ERN1 O75460 2/20 0.44
TUBB1 Q9H4B7 1/20 0.43
ATM Q13315 2/20 0.43
KDM4E B2RXH2 1/20 0.43
LDHA P00338 1/20 0.42
TSHR P16473 1/20 0.42
POLB P06746 1/20 0.41
CYP19A1 P11511 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
PTGS1 P23219 1/20 0.41
ABCB1 P08183 1/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29640498 1.00 CA2 (0.48) CA2ALDH1A1PPARGPPARDPPARA
SCHEMBL23457668 0.85 TACR2 (0.45) ALDH1A1TUBB1ATMTSHRPOLB
SCHEMBL20734996 0.84 CA2 (0.50) CA2ALDH1A1PPARGPPARDPPARA
SCHEMBL291363 0.83 CA2 (0.68) CA2ALDH1A1PPARGPPARDPPARA
SCHEMBL19789577 0.83 CA2 (0.48) CA2ALDH1A1PPARGPPARDPPARA
SCHEMBL29639720 0.83 CA2 (0.48) CA2ALDH1A1PPARGPPARDPPARA
SCHEMBL2818747 0.81 ATM (0.50) CA2ALDH1A1ATMKDM4EPOLB
SCHEMBL31344420 0.80 ALDH1A1 (0.75) ALDH1A1PPARGPPARDPPARAKDM4E
SCHEMBL29813 0.80 ALDH1A1 (0.75) ALDH1A1PPARGPPARDPPARAKDM4E
SCHEMBL28276706 0.79 ALDH1A1 (0.73) ALDH1A1PPARGPPARDPPARAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12252465-B2 Enol ether properfume FIRMENICH SA (CH) 2025-03-18 US disclosed
US-20240059640-A1 Enol Ether Properfume FIRMENICH SA (CH) 2024-02-22 US disclosed
EP-4007748-A1 ENOL ETHER PROPERFUME Firmenich SA (CH) 2022-06-08 EP disclosed
WO-2021110680-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2021-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12252465-B2 Enol ether properfume CYP2E1, ETFB, ECI1 CA2 4316/4885ALDH1A1 111/4885PPARG 677/4885
US-20240059640-A1 Enol Ether Properfume CYP2E1, ETFB, ECI1 CA2 4316/4885ALDH1A1 111/4885PPARG 677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.