Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23459351 | 0.87 | L3MBTL1 (0.37) | MAPTMEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL16616309 | 0.79 | SSTR5 (0.49) | MAPTLMNAFFAR4NR3C1SSTR5 | |
| SCHEMBL16616252 | 0.78 | SLC6A3 (0.50) | MAPTMEN1KMT2AHSD17B10CYP1A2 | |
| SCHEMBL7797903 | 0.76 | TSHR (0.43) | MAPTMEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL20562654 | 0.75 | HSD17B10 (0.44) | MAPTMEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL16960532 | 0.75 | MAPK1 (0.43) | MAPTMAPK1HSD17B10L3MBTL1CYP1A2 | |
| SCHEMBL19859187 | 0.75 | L3MBTL1 (0.42) | MAPTMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL23459421 | 0.74 | ALDH1A1 (0.44) | MEN1KMT2AMAPK1POLBNPSR1 | |
| SCHEMBL23586689 | 0.73 | TSHR (0.41) | MAPTMEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL3097800 | 0.72 | SSTR5 (0.48) | MAPTMEN1KMT2AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230050965-A1 | SSTR5 ANTAGONISTS | KALLYOPE, INC. | 2023-02-16 | — | — | US | disclosed |
| EP-4069708-A1 | SSTR5 ANTAGONISTS | Kallyope, Inc. (US) | 2022-10-12 | — | — | EP | disclosed |
| WO-2021113363-A1 | SSTR5 ANTAGONISTS | KALLYOPE, INC. (US) | 2021-06-10 | — | — | WO | disclosed |
| WO-2021113363-A1 | SSTR5 ANTAGONISTS | KALLYOPE, INC. (US) | 2021-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230050965-A1 | SSTR5 ANTAGONISTS | SSTR5, GLP1R, GPR119 | MAPT 1483/4885MEN1 2406/4885KMT2A 2300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.